Evidence map›Paper›PMID 33412895›Full record

ArticleCell transplantation

Low-Intensity Pulsed Ultrasound Promotes Autophagy-Mediated Migration of Mesenchymal Stem Cells and Cartilage Repair.

Peng Xia, Xinwei Wang, Qi Wang, Xiaoju Wang, Qiang Lin, Kai Cheng, Xueping Li

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Peng XiaDepartment of Rehabilitation Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, P. R. China.
Xinwei WangDepartment of Rehabilitation Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, P. R. China.
Qi WangDepartment of Rehabilitation Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, P. R. China.
Xiaoju WangDepartment of Rehabilitation Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, P. R. China.
Qiang LinDepartment of Rehabilitation Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, P. R. China.
Kai ChengDepartment of Rehabilitation Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, P. R. China.
Xueping LiDepartment of Rehabilitation Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, P. R. China.ORCID 0000-0003-3891-3385
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cell (MSC) migration is promoted by low-intensity pulsed ultrasound (LIPUS), but its mechanism is unclear. Since autophagy is known to regulate cell migration, our study aimed to investigate if LIPUS promotes the migration of MSCs via autophagy regulation. We also aimed to investigate the effects of intra-articular injection of MSCs following LIPUS stimulation on osteoarthritis (OA) cartilage. For the

Indexed as

Ultrasonic WavesAnimalsAutophagyCartilage, ArticularMaleMesenchymal Stem CellsOsteoarthritisRatsRats, Sprague-Dawleyautophagymesenchymal stem cellmigrationultrasound

Identifiers

PMID33412895
PMCPMC7797574
OpenAlexW3119399049

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.