Evidence map›Paper›PMID 33412762›Full record

ArticleGenomics & informatics2020

BaSDAS: a web-based pooled CRISPR-Cas9 knockout screening data analysis system.

Young-Kyu Park, Byoung-Ha Yoon, Seung-Jin Park, Byung Kwon Kim, Seon-Young Kim

Open access · diamondAbstract read
In one paragraph

Article in Genomics & informatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Young-Kyu ParkOmicsPia Co., Ltd., Daejeon 34867, Korea.
Byoung-Ha YoonPersonalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.
Seung-Jin ParkPersonalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.
Byung Kwon KimOmicsPia Co., Ltd., Daejeon 34867, Korea.
Seon-Young KimPersonalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.
Korea Research Institute of Bioscience and Biotechnology · KR

Funding

KRIBB Research Initiative ProgramNational Research Foundation of Korea 2014M3C9A3068554National Research Foundation of Korea 2017MBA9B5060884
6 · The paper itself

Abstract

We developed the BaSDAS (Barcode-Seq Data Analysis System), a GUI-based pooled knockout screening data analysis system, to facilitate the analysis of pooled knockout screen data easily and effectively by researchers with limited bioinformatics skills. The BaSDAS supports the analysis of various pooled screening libraries, including yeast, human, and mouse libraries, and provides many useful statistical and visualization functions with a user-friendly web interface for convenience. We expect that BaSDAS will be a useful tool for the analysis of genome-wide screening data and will support the development of novel drugs based on functional genomics information.

Indexed as

CRISPR-Cas Systemsdata visualizationgene editinggene expressionpathway analysis

Identifiers

PMID33412762
PMCPMC7808871
OpenAlexW3117408708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.