ArticleThrombosis and haemostasis2021
Platelets are Hyperactivated but Show Reduced Glycoprotein VI Reactivity in COVID-19 Patients.
Abstract readLetterComment
In one paragraph
Article in Thrombosis and haemostasis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Targeting GPVI with glenzocimab in COVID-19 patients: Results from a randomized clinical trial.PloS one · 2024Trial
- Differential platelet protein release profiles in community-acquired pneumonia and COVID-19.ERJ open research · 2025Article
- Role of Liver Kinase 1B in Platelet Activation and Host Defense DuringInternational journal of molecular sciences · 2025Article
- High-Dimensional Single-Cell Mass Cytometry Demonstrates Differential Platelet Functional Phenotypes in Infants With Congenital Heart Disease.Arteriosclerosis, thrombosis, and vascular biology · 2024Article
- Proteomic profiling of neutrophils and plasma in community-acquired pneumonia reveals crucial proteins in diverse biological pathways linked to clinical outcome.Frontiers in immunology · 2024Article
- The Ways of the Virus: Interactions of Platelets and Red Blood Cells with SARS-CoV-2, and Their Potential Pathophysiological Significance in COVID-19.International journal of molecular sciences · 2023Review
- Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death.Research and practice in thrombosis and haemostasis · 2023Article
- Circulating cellular clusters are associated with thrombotic complications and clinical outcomes in COVID-19.iScience · 2023Article
- Inhibition of SARS-CoV-2-mediated thromboinflammation by CLEC2.Fc.EMBO molecular medicine · 2023Article
- Alterations in platelet proteome signature and impaired platelet integrin αJournal of thrombosis and haemostasis : JTH · 2023Article
- In silico investigation ofJournal of ginseng research · 2023Article
- Early SARS-CoV-2 infection: Platelet-neutrophil complexes and platelet function.Research and practice in thrombosis and haemostasis · 2023Article
- Platelet Reactivity and Inflammatory Phenotype Induced by Full-Length Spike SARS-CoV-2 Protein and Its RBD Domain.International journal of molecular sciences · 2022Article
- The homophilic CD84 receptor is upregulated on platelets in COVID-19 and sepsis.Thrombosis research · 2022Article
- Understanding COVID-19-associated coagulopathy.Nature reviews. Immunology · 2022Review
- The Platelet Lipidome Is Altered in Patients with COVID-19 and Correlates with Platelet Reactivity.Thrombosis and haemostasis · 2022Article
- Platelet activation and partial desensitization are associated with viral xenophagy in patients with severe COVID-19.Blood advances · 2022Article
- Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 Thrombosis Biomarkers Colloquium.Nature reviews. Cardiology · 2022Review
- Activated Platelets and Platelet-Derived Extracellular Vesicles Mediate COVID-19-Associated Immunothrombosis.Frontiers in cell and developmental biology · 2022Review
- Platelets in Viral Infections - Brave Soldiers or Trojan Horses.Frontiers in immunology · 2022Review
Corrections and comments
- Comment on
Authors and funding
13 authors.
Valentine LéopoldCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Liza PereverzevaCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Alex R SchuurmanCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Tom D Y ReijndersCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Anno SarisCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Justin de BrabanderCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Christine C A van LingeCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Renée A DoumaDepartment of Internal Medicine, Flevo Hospital, Almere, The Netherlands.
Osoul ChouchaneCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Rienk NieuwlandLaboratory of Experimental Clinical Chemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
W Joost WiersingaCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Cornelis van 't VeerCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Tom van der PollCenter of Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Funding
Bourse à la mobilité Institut ServierEcole de l'INSERM Liliane Bettencourt Institut National de la Santé et de la Recherche MédicaleFAIR # 847786 Horizon 2020 Framework ProgrammeJPI-AMR/ZonMW # 547001008 Joint Programming Initiative on Antimicrobial ResistanceNACTAR ( # 16447) Nederlandse Organisatie voor Wetenschappelijk OnderzoekUnited States Assistance Publique - Hôpitaux de Paris
Abstract
PubMed holds no abstract for this paper.
Indexed as
Blood PlateletsCOVID-19HumansPlatelet ActivationPlatelet Membrane GlycoproteinsSARS-CoV-2Platelet Membrane Glycoproteins
Identifiers
PMID
33412595What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.