Evidence map›Paper›PMID 33412144›Full record

ArticleClinica chimica acta; international journal of clinical chemistry2021

The path to the standardization of PTH: Is this a realistic possibility? a position paper of the IFCC C-BM.

Etienne Cavalier, Samuel Vasikaran, Harjit P Bhattoa, Annemieke C Heijboer, Konstantinos Makris, Candice Z Ulmer

Open access · greenAbstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinica chimica acta; international journal of clinical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 6 countries.

Etienne CavalierDepartment of Clinical Chemistry, University of Liège, CHU de Liège, Domaine du Sart-Tilman, B-4000 Liège, Belgium. Electronic address: Etienne.cavalier@chuliege.be.
Samuel VasikaranPathWest Laboratory Medicine, Fiona Stanley Hospital, Murdoch, WA, Australia.
Harjit P BhattoaDepartment of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen Hungary.
Annemieke C HeijboerDepartment of Clinical Chemistry, Endocrine Laboratory, Amsterdam Gastroenterology & Metabolism, Vrije Universiteit Amsterdam and University of Amsterdam, Amsterdam UMC, Amsterdam, Netherlands.
Konstantinos MakrisClinical Biochemistry Department, KAT General Hospital, 14561 Athens, Greece; Laboratory for Research of the Musculoskeletal System "Th. Garofalidis", Medical School, University of Athens, Athens, Greece.
Candice Z UlmerClinical Chemistry Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Buford, Atlanta, GA, USA.
Amsterdam University Medical Centers · NLCenters for Disease Control and Prevention · USFiona Stanley Hospital · AUNational and Kapodistrian University of Athens · GRUniversity of Debrecen · HUUniversity of Liège · BE

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Parathyroid hormone (PTH) determination is of greatest importance for patients suffering from parathyroid gland disorders and for the follow-up of bone turnover in patients suffering from chronic kidney disease (CKD). Two generations of PTH assays are simultaneously present on the market for PTH quantification. As these assays are not yet standardized, this results in a significant level of confusion in the care of CKD patients. One key objective of the IFCC Committee for Bone Metabolism is to improve this situation. In this position paper, we will highlight the current state of PTH testing and propose a pathway to ultimately overcome issues resulting from PTH assay variability.

Indexed as

Kidney Failure, ChronicRenal Insufficiency, ChronicHumansImmunoassayParathyroid HormoneReference StandardsParathyroid HormoneImmunoassaysParathyroid hormoneStandardization

Identifiers

PMID33412144
PMCPMC7920929
OpenAlexW3118277168

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.