Evidence map›Paper›PMID 33411966›Full record

ArticleInternational journal of clinical practice2021

A case report of rhabdomyolysis caused by the use of roxadustat in the treatment caused by renal anaemia.

Qin Yang, Xin Wang

Abstract readCase Reports
In one paragraph

Article in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Roxadustat: Do we know all the answers?Biomolecules & biomedicine · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Qin YangDepartment of Nephrology, Affiliated Zhongshan Hospital of Dalian University, Dalian, China.ORCID https://orcid.org/0000-0003-3566-8898
Xin WangDepartment of Nephrology, Affiliated Zhongshan Hospital of Dalian University, Dalian, China.ORCID https://orcid.org/0000-0001-6602-1355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

case presentationIn this case, we share a case of one of our patients developed rhabdomyolysis after he was administered roxadustat to treat anaemia caused by chronic renal failure. DISCUSSION: More than 1.2 million people died from chronic kidney damage (CKD) globally, in 2017. Anaemia is a common complication of CKD. Roxadustat is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor that stimulates erythropoiesis and regulates iron metabolism. Roxadustat is often used to treat anaemia caused by renal failure. Its adverse effects include high blood pressure, myocardial infarction, heart failure, high potassium, and dizziness; however, there are no reports about rhabdomyolysis associated with roxadustat.

conclusionPhysicians should be alert about the occurrence of rhabdomyolysis when roxadustat is used.

Indexed as

AnemiaRenal Insufficiency, ChronicRhabdomyolysisGlycineHumansIsoquinolinesMaleGlycineIsoquinolinesroxadustat

Identifiers

PMID33411966
PMCPMC8243928

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.