Evidence map›Paper›PMID 33411159›Full record

ArticleBrain imaging and behavior2021

White matter changes following experimental pediatric traumatic brain injury: an advanced diffusion-weighted imaging investigation.

Akram Zamani, Terence J O'Brien, Jeff Kershaw, Leigh A Johnston, Bridgette D Semple, David K Wright

Abstract read
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In one paragraph

Article in Brain imaging and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Akram ZamaniDepartment of Neuroscience, Central Clinical School, Monash University, The Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.
Terence J O'BrienDepartment of Neuroscience, Central Clinical School, Monash University, The Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.
Jeff KershawApplied MRI Research, National Institute of Radiological Sciences, QST, Chiba, Japan.
Leigh A JohnstonMelbourne Brain Centre Imaging Unit, Department of Biomedical Engineering, The University of Melbourne, 3010, Parkville, VIC, Australia.
Bridgette D SempleDepartment of Neuroscience, Central Clinical School, Monash University, The Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.
David K WrightDepartment of Neuroscience, Central Clinical School, Monash University, The Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia. david.wright@monash.edu.ORCID http://orcid.org/0000-0002-7535-8651
The Alfred Hospital · AUThe Royal Melbourne Hospital · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric traumatic brain injury (pTBI) is a major community health concern. Due to ongoing maturation, injury to the brain at a young age can have devastating consequences in later life. However, how pTBI affects brain development, including white matter maturation, is still poorly understood. Here, we used advanced diffusion weighted imaging (DWI) to assess chronic white matter changes after experimental pTBI. Mice at post-natal day 21 sustained a TBI using the controlled cortical impact model and magnetic resonance imaging (MRI) was performed at 6 months post-injury using a 4.7 T Bruker scanner. Four diffusion shells with 81 directions and b-values of 1000, 3000, 5000, and 7000s/mm

Indexed as

Brain Injuries, TraumaticWhite MatterAnimalsBrainChildDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingHumansMagnetic Resonance ImagingMicefiber densitypediatric TBIwhite matter

Identifiers

PMID33411159
OpenAlexW3120670152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.