Evidence map›Paper›PMID 33411082›Full record

ReviewCancer metastasis reviews2021

Role of myeloid-derived suppressor cells in metastasis.

Kathryn Cole, Kristina Pravoverov, James E Talmadge

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cancer metastasis reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 36 citations in OpenAlex.

  1. Targeting FAPActa pharmaceutica Sinica. B · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Metastasis-promoting functions of myeloid cells.Cancer metastasis reviews · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
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  15. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kathryn ColeDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, 68198, USA.ORCID 0000-0002-0452-9636
Kristina PravoverovDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, 68198, USA.ORCID 0000-0002-2562-7315
James E TalmadgeDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, 68198, USA. jtalmadg@unmc.edu.ORCID 0000-0002-6328-6056
University of Nebraska Medical Center · USNebraska Medical Center · US

Funding

UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Joann B. Sweasy · 1985 to 2026
$55.0M
NIH HHS P30 CA036727
6 · The paper itself

Abstract

The spread of primary tumor cells to distant organs, termed metastasis, is the principal cause of cancer mortality and is a critical therapeutic target in oncology. Thus, a better understanding of metastatic progression is critical for improved therapeutic approaches requiring insight into the timing of tumor cell dissemination and seeding of distant organs, which can lead to the formation of occult lesions. However, due to limitations in imaging techniques, primary tumors can only be detected when they reach a relatively large size (e.g., > 1 cm

Indexed as

AnimalsHumansMyeloid-Derived Suppressor CellsNeoplasm MetastasisNeoplasmsTranslational Research, BiomedicalCirculating tumor cellsDormancyMetastasisMyeloid-derived suppressor cellsPre-metastatic niche

Identifiers

PMID33411082
OpenAlexW3119974568

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.