ArticlePediatric nephrology (Berlin, Germany)2021
Acute kidney injury in children hospitalized for acute gastroenteritis: prevalence and risk factors.
Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Acute kidney injury due to diarrhoeal diseases in children: a systematic review.BMJ paediatrics open · 2026Pooled it
- Prevalence of common diarrheagenic enterobacteriaceae in Iran (2000-2023): a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Early, frequent, yet reversible: acute kidney injury after hematopoietic stem cell transplantation in pediatric Fanconi anemia and long-term renal outcomes.Pediatric nephrology (Berlin, Germany) · 2026Article
- Risk of Acute Kidney Injury inOpen forum infectious diseases · 2026Article
- AKI and Mortality in Children Hospitalized With Malnutrition.Kidney international reports · 2026Article
- Prevalence and risk factors for acute kidney injury at the diagnosis of juvenile idiopathic arthritis in children and its long-term implications for kidney health.Pediatric nephrology (Berlin, Germany) · 2026Article
- Vibriosis-associated acute kidney injury : Incidence and outcome.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Prevalence and factors associated with acute kidney injury in children presenting to the emergency department with a first tonic-clonic seizure: an exploratory study.European journal of pediatrics · 2026Article
- Novel cause of Acute Kidney Injury and its Predictors of Mortality.Pakistan journal of medical sciences · 2026Article
- Severe red kidney beans toxicity in an 8-year-old girl: a rare case of hypovolemic shock and prerenal acute kidney injury.International journal of emergency medicine · 2026Article
- Acute Kidney Injury in Children with Polyuria: A Systematic Review.Journal of clinical medicine · 2026Review
- A novel age-norm-capped baseline serum creatinine approach for acute kidney injury diagnosis in critically Ill children: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- The relevance of acute kidney injury in dehydrated children.Frontiers in pediatrics · 2025Review
- Heart rate to identify non-febrile children with dehydration and acute kidney injury in emergency department: a prospective validation study.European journal of pediatrics · 2024Article
- Contrast-Enhanced Ultrasound (CEUS) and Ultra-Microangiography (UMA) in Critically Ill Children with Acute Kidney Injury.Children (Basel, Switzerland) · 2024Review
- Acute Kidney Injury in Children: A Focus for the General Pediatrician.Children (Basel, Switzerland) · 2024Review
- Editorial on the Special Issue "Advances in Pediatric Acute Kidney Injury".Children (Basel, Switzerland) · 2024Article
- Acute kidney injury in infants hospitalized for viral bronchiolitis.European journal of pediatrics · 2023Article
- Acute and chronic kidney complications in children with type 1 diabetes mellitus.Pediatric nephrology (Berlin, Germany) · 2023Review
- Factors Associated with Acute Kidney Injury among Children with Severe Malaria at Kiryandongo General Hospital, Uganda.International journal of pediatrics · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to evaluate prevalence of acute kidney injury (AKI) and its risk factors in children hospitalized for acute gastroenteritis (AGE) to identify early predictors of AKI.
methodsWe retrospectively collected clinical and biochemical data of 114 children (57.9% male; mean age 2.9 ± 2.8 years) hospitalized for AGE. AKI was defined according to Kidney Disease/Improving Global Outcomes creatinine criteria. We considered basal serum creatinine as value of creatinine estimated with Hoste (age) equation assuming basal eGFRs were median age-based eGFR normative values for children ≤ 2 years of age, and eGFR 120 mL/min/1.73m
resultsAKI was found in 28/114 (24.6%) patients. No patients required hemodialysis, 2 (1.8%) reached AKI stage 3, 2 (1.8%) AKI stage 2, and 24 (21.0%) AKI stage 1. Mean length of stay was 3.6 ± 1.2, 5.0 ± 1.8, and 10.5 ± 5.8 days, for patients with no, mild, and severe AKI (p < 0.001), respectively. Duration of symptoms before hospitalization (OR = 2.5; 95% CI = 1.3-5.0; p = 0.006), dehydration > 5% (OR = 43.1; 95% CI = 5.4-344.1; p = < 0.001), and serum bicarbonate levels (OR = 1.6; 95% CI = 1.2-2.1; p = 0.001) were independent predictors of AKI.
conclusionsAbout one quarter of patients hospitalized for AGE may suffer from AKI with a longer stay for patients with more severe AKI. Particular attention, however, should be paid to volemia and kidney health of patients with AGE especially in the presence of increased duration of symptoms before hospitalization, dehydration, and lower serum bicarbonate levels.
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