ReviewPediatric nephrology (Berlin, Germany)2021
Acute kidney injury and aging.
Review in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 69 citations in OpenAlex.
- Klotho-Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- The Aging Kidney and Acute Kidney Injury.Journal of the American Society of Nephrology : JASN · 2026Review
- Review
- A nomogram model for predicting acute kidney injury in critically ill patients with upper gastrointestinal bleeding: a study based on the MIMIC-IV database and external validation.BMC gastroenterology · 2026Article
- Prevalence and risk factors of acute kidney injury in patients with hip fractures.Journal of perioperative practice · 2026Observational
- Perioperative acute kidney injury: current prevention, detection, and management strategies.Journal of anesthesia · 2026Review
- Kidney Outcomes in ANCA-Glomerulonephritis According to Induction Immunosuppression and Histopathology.Kidney international reports · 2026Article
- Article
- Forecasting ICU Acute Kidney Injury with Actionable Lead Time Using Interpretable Machine Learning: Development and Multi-Center Validation.Journal of clinical medicine · 2026Article
- Application of XGBoost and logistic regression in predicting 90 days mortality for elderly severe acute renal failure patients.Scientific reports · 2026Article
- A Commentary on "Accelerated biological aging and postoperative acute kidney injury in surgical patients".International journal of surgery (London, England) · 2026Article
- Association between inflammatory burden index combined with D-dimer and acute kidney injury in elderly patients.Frontiers in medicine · 2026Article
- Development and Validation of a Machine Learning Model for Predicting Serum Creatinine-Defined Acute Kidney Injury in Older Adults After Cardiac Surgery.Clinical interventions in aging · 2026Article
- Identification of Risk Factors and Prediction Models for Acute Kidney Injury in Hospitalized Elderly Patients with Heart Failure.Clinical interventions in aging · 2026Article
- Aging Mediates Inflammatory Transformation of Kidney-Resident Macrophages via Thrombospondin-1 Signaling.Immune network · 2025Article
- Development and validation of a nomogram for predicting acute kidney injury in elderly patients in intensive care unit.Renal failure · 2025Article
- Analysis of prognostic risk factors in critically ill elderly patients with sepsis-associated acute kidney injury.BMC nephrology · 2025Article
- Dasatinib and Quercetin Combination Increased Kidney Damage in Acute Folic Acid-Induced Experimental Nephropathy.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Acute kidney injury in hospitalized patients with real-life analysis of incidence and clinical impact in Italian hospitals (the SIN-AKI study).Scientific reports · 2025Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Our aging population is growing and developing treatments for age-related diseases such as Alzheimer's and Parkinson's disease has taken on an increasing urgency and is accompanied by high public awareness. The already high and rising incidence of acute kidney injury (AKI) in the elderly, however, has received relatively little attention despite the potentially fatal outcomes associated with an episode of AKI in this age group. When discussing AKI and aging, one should consider two aspects: first, elderly patients have an increased susceptibility to an AKI episode, and second, they have decreased kidney repair after AKI given the high incidence of progression to chronic kidney disease (CKD). It is unclear if the same factors that drive the increased susceptibility to AKI could be playing a role in the decreased repair capacity or if they are totally different and unrelated. This review will examine current knowledge on the risk factors for the increased susceptibility to AKI in the elderly and will also explore potential aspects that might contribute to a decreased kidney repair response in this age group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.