ArticleMicrobial ecology2021
Population Structure and Multidrug Resistance of Non-O1/Non-O139 Vibrio cholerae in Freshwater Rivers in Zhejiang, China.
Article in Microbial ecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Vibrio cholerae in Water Environments: A Systematic Review and Meta-Analysis.Environmental microbiology reports · 2025Pooled it
- Integrated Phenotypic and Genomic Analysis of Antimicrobial Resistance, Virulence, and Phylogeny inMicroorganisms · 2026Article
- Genomic characterization of clinical and environmentalFrontiers in microbiology · 2026Article
- Genomic Analysis and Virulence Features of Vibrio cholerae Non-O1/Non-O139 Harbouring CARB-Type β-Lactamases From Freshwater Bodies, Argentina.Environmental microbiology reports · 2025Article
- Genomic evidence of two-staged transmission of the early seventh cholera pandemic.Nature communications · 2024Article
- Whole Genome Sequencing of a Non-O1/O139-GroupInfection and drug resistance · 2024Article
- Emergence and genomic insights of non-pandemic O1Microbiology spectrum · 2023Article
- Article
- Genomic Epidemiology of Vibrio cholerae O139, Zhejiang Province, China, 1994-2018.Emerging infectious diseases · 2022Article
- Distribution and Molecular Characteristics ofMicroorganisms · 2022Article
- Antimicrobial Resistance and Molecular Characterization ofFrontiers in cellular and infection microbiology · 2021Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 2 countries.
Funding
Abstract
To understand the environmental reservoirs of Vibrio cholerae and their public health significance, we surveyed freshwater samples from rivers in two cities (Jiaxing [JX] and Jiande [JD]) in Zhejiang, China. A total of 26 sampling locations were selected, and river water was sampled 456 times from 2015 to 2016 yielding 200 V. cholerae isolates, all of which were non-O1/non-O139. The average isolation rate was 47.3% and 39.1% in JX and JD, respectively. Antibiotic resistance profiles of the V. cholerae isolates were examined with nonsusceptibility to cefazolin (68.70%, 79/115) being most common, followed by ampicillin (47.83%, 55/115) and imipenem (27.83%, 32/115). Forty-two isolates (36.52%, 42/115) were defined as multidrug resistant (MDR). The presence of virulence genes was also determined, and the majority of the isolates were positive for toxR (198/200, 99%) and hlyA (196/200, 98%) with few other virulence genes observed. The population structure of the V. cholerae non-O1/non-O139 sampled was examined using multilocus sequence typing (MLST) with 200 isolates assigned to 128 STs and 6 subpopulations. The non-O1/non-O139 V. cholerae population in JX was more varied than in JD. By clonal complexes (CCs), 31 CCs that contained isolates from this study were shared with other parts of China and/or other countries, suggesting widespread presence of some non-O1/non-O139 clones. Drug resistance profiles differed between subpopulations. The findings suggest that non-O1/non-O139 V. cholerae in the freshwater environment is a potential source of human infections. Routine surveillance of non-O1/non-O139 V. cholerae in freshwater rivers will be of importance to public health.
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