Evidence map›Paper›PMID 33410656›Full record

ArticleACS applied materials & interfaces2021

Divalent Cation Dependence Enhances Dopamine Aptamer Biosensing.

Nako Nakatsuka, John M Abendroth, Kyung-Ae Yang, Anne M Andrews

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 79 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nako NakatsukaDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID http://orcid.org/0000-0001-8248-5248
John M AbendrothDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID http://orcid.org/0000-0002-2369-4311
Kyung-Ae YangDivision of Experimental Therapeutics, Department of Medicine, Columbia University, New York, New York 10032, United States.ORCID http://orcid.org/0000-0001-5575-4107
Anne M AndrewsDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID http://orcid.org/0000-0002-1961-4833
California NanoSystems Institute · USColumbia University · US

Funding

Micro- to Nanoscale Neurochemical SensorsR01DA045550 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ANDREWS, ANNE MILASINCIC · 2017 to 2021
$5.8M
NIDA NIH HHS R01 DA045550
6 · The paper itself

Abstract

Oligonucleotide receptors (aptamers), which change conformation upon target recognition, enable electronic biosensing under high ionic-strength conditions when coupled to field-effect transistors (FETs). Because highly negatively charged aptamer backbones are influenced by ion content and concentration, biosensor performance and target sensitivities were evaluated under application conditions. For a recently identified dopamine aptamer, physiological concentrations of Mg

Indexed as

Aptamers, NucleotideBenzothiazolesBiosensing TechniquesCalciumDopamineElectrochemical TechniquesG-QuadruplexesMagnesiumSerotoninTransistors, ElectronicAptamers, NucleotideBenzothiazolesCalciumDopamineMagnesiumSerotoninthioflavin TCa2+circular dichroism spectroscopyDebye lengthfield-effect transistorMg2+neurotransmitteroligonucleotidesserotonin

Identifiers

PMID33410656
PMCPMC7933093
OpenAlexW3118759612

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.