Evidence map›Paper›PMID 33410478›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2021

Contribution of Sleep Disruption and Sedentary Behavior to Fatigue in Survivors of Allogeneic Hematopoietic Cell Transplant.

Ashley M Nelson, Kelly A Hyland, Brent Small, Brittany Kennedy, Asmita Mishra, Aasha I Hoogland, Hailey W Bulls, Heather S L Jim, Paul B Jacobsen

Open access · greenAbstract read
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ashley M NelsonDepartment of Psychiatry, Harvard Medical School/Massachusetts General Hospital, MA, USA.ORCID 0000-0003-1742-3280
Kelly A HylandDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Brent SmallDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0002-7444-4689
Brittany KennedyDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Asmita MishraDepartment of Blood and Marrow Transplant and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL, USA.
Aasha I HooglandDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Hailey W BullsDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Heather S L JimDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Paul B JacobsenHealthcare Delivery Research Program, National Cancer Institute, Bethesda, MD, USA.
Moffitt Cancer Center · USUniversity of South Florida · USHarvard University · USNational Cancer Institute · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
Training in Oncology Population Sciences (TOPS)T32CA092203 · NCI · DANA-FARBER CANCER INST · PI Nancy L Keating, JENNIFER W MACK · 2018 to 2026
$3.7M
NCI NIH HHS P30 CA076292NCI NIH HHS T32 CA092203
6 · The paper itself

Abstract

backgroundFatigue is a prominent quality of life concern among recipients of hematopoietic cell transplantation (HCT). PURPOSE: The present study investigated whether objectively measured sleep efficiency and sedentary behavior are related to greater reports of fatigue.

methodsEighty-two allogeneic HCT recipients who were 1-5 years post-transplant and returning for a follow-up visit participated (age M = 56, 52% female, 56% leukemia). They wore an actigraph assessing sleep efficiency and sedentary behavior for one week and completed an electronic log assessing fatigue each evening during the same period.

resultsTwenty-six percent of patients reported clinically meaningful fatigue. On average, fatigue was mild (M = 2.5 on 0-10 scale, SD = 2.0), sleep was disturbed (sleep efficiency M = 78.9%, SD = 8.9), and patients spent the majority of time in sedentary (M = 55.4%, SD = 10.2) or light (M = 35.9%, SD = 8.6) activity. Multilevel model analysis of between-person differences indicated that patients who experienced less efficient sleep the previous evening provided greater evening reports of average fatigue, b = -0.06, 95% CI (-0.11, -0.01). Similarly, within-person analyses indicated that when patients experienced less efficient sleep the previous evening or were more sedentary as compared to their average, they provided greater evening reports of average fatigue, b = -0.02, 95% CI (-0.05, -0.004); b = 4.46, 95% CI (1.95, 6.97), respectively.

conclusionsFindings demonstrate that poor sleep and daily sedentary behavior are related to evening reports of fatigue and should be considered modifiable targets for intervention.

Indexed as

Hematopoietic Stem Cell TransplantationSedentary BehaviorFatigueFemaleHumansMaleQuality of LifeSleepSurvivorsActigraphyFatigueHematopoietic cell transplantationPsycho-oncologySedentary behaviorSleep

Identifiers

PMID33410478
PMCPMC8517217
OpenAlexW3120455080

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.