Does the CCR5-Δ32 mutation explain the variable coronavirus-2019 pandemic statistics in Europe?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. Role of ACE1, ACE2, and CCR5-Δ32 Polymorphisms in the Transmission of SARS-CoV-2 to Intimate Contacts.Biology · 2025
   Article
2. Investigating the Potential Impact of CCR5-Δ32 Variant on COVID-19 Outcome: A Case-Control Study in Iranian Population.Iranian journal of public health · 2024
   Article
3. Allelic Variations in the Human GenesInternational journal of molecular sciences · 2022
   Article
4. Host polymorphisms and COVID-19 infection.Advances in clinical chemistry · 2022
   Article
5. Could the CCR5-Delta32 mutation be protective in SARS-CoV-2 infection?Physiological research · 2021
   Article
6. Differential mortality of infectious disease in Italian polities: COVID-19, past plague epidemics, and currently endemic respiratory disease.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021
   Article
7. Variant-genetic and transcript-expression analysis showed a role for the chemokine-receptor CCR5 in COVID-19 severity.International immunopharmacology · 2021
   Article
8. Update on human genetic susceptibility to COVID-19: susceptibility to virus and response.Human genomics · 2021
   Article

Corrections and comments

• Comment on
  The host's angiotensin-converting enzyme polymorphism may explain epidemiological findings in COVID-19 infections.2020
• Comment on
  COVID-19 infections are also affected by human ACE1 D/I polymorphism.2020
• Comment on
  No significant correlation between ACE Ins/Del genetic polymorphism and COVID-19 infection.2020
• Comment on
  An evidence for correlation between the glutathione S-transferase T1 (GSTT1) polymorphism and outcome of COVID-19.2020

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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