Evidence map›Paper›PMID 33409906›Full record

Observational studyHormones (Athens, Greece)2021

Metabolic profile of patients with isolated systolic hypertension.

J A Papadakis, P Ioannou, V Theodorakopoulou, K Papanikolaou, G Vrentzos

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Hormones (Athens, Greece), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

J A PapadakisHypertension Unit (ESH Excellence Center), Department of Internal Medicine, University Hospital of Heraklion, Stavrakia and Voutes Crossroads, 71110, Heraklion, Crete, Greece.
P IoannouHypertension Unit (ESH Excellence Center), Department of Internal Medicine, University Hospital of Heraklion, Stavrakia and Voutes Crossroads, 71110, Heraklion, Crete, Greece. p.ioannou@med.uoc.gr.ORCID http://orcid.org/0000-0003-1082-5674
V TheodorakopoulouHypertension Unit (ESH Excellence Center), Department of Internal Medicine, University Hospital of Heraklion, Stavrakia and Voutes Crossroads, 71110, Heraklion, Crete, Greece.
K PapanikolaouHypertension Unit (ESH Excellence Center), Department of Internal Medicine, University Hospital of Heraklion, Stavrakia and Voutes Crossroads, 71110, Heraklion, Crete, Greece.
G VrentzosHypertension Unit (ESH Excellence Center), Department of Internal Medicine, University Hospital of Heraklion, Stavrakia and Voutes Crossroads, 71110, Heraklion, Crete, Greece.
University Hospital of Heraklion · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PURPOSE/

objectiveWhile hypertension is an important contributor to cardiovascular disease (CVD) and its treatment has well-established mortality benefits, there is uncertainty as regards the management of isolated systolic hypertension (ISH). Furthermore, the association of ISH with CVD and mortality has been established, but the metabolic characteristics of the affected population have not as yet been adequately described. The aim of this study was to describe the metabolic profiles of patients with ISH.

methodsAn observational study of patients attending the Hypertension Unit of the University Hospital of Heraklion, Crete, Greece, was performed.

resultsIn total, 809 hypertensive patients not on any antihypertensive treatment were identified. Among them, 44.7% were men, aged 55.6 ± 12.5 years, while 29.7% of both men and women were smokers. Systolic blood pressure was 161.3 ± 15.8 mmHg and diastolic blood pressure was 96.1 ± 11.3 mmHg. Body mass index (BMI) was 31 ± 5.3 kg/m

conclusionPatients with ISH were older, with lower SBP, total cholesterol, and LDL and higher pulse pressure and higher prevalence of diabetes.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2HypertensionBlood PressureCholesterolFemaleHumansMaleMetabolomeRisk FactorsCholesterolHypertensionIsolated systolic hypertensionMetabolic

Identifiers

PMID33409906
OpenAlexW3120732321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.