Evidence map›Paper›PMID 33409848›Full record

Observational studyUpdates in surgery2021

Anastomosis configuration and technique following ileocaecal resection for Crohn's disease: a multicentre study.

Valerio Celentano, Gianluca Pellino, Antonino Spinelli, Francesco Selvaggi, SICCR Current status of Crohn’s disease surgery collaborative, Valerio Celentano, Gianluca Pellino, Matteo Rottoli, Gilberto Poggioli, Giuseppe Sica and 68 more

Open access · greenAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Updates in surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Stapled End-To-Side Ileocolic Anastomosis in Crohn's Disease: Old Dog, Reliable Tricks? A Retrospective Two-Center Cohort Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Anastomotic Considerations in Crohn's Disease.Clinics in colon and rectal surgery · 2023
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. The impact of preoperative total parenteral nutrition on the surgical complications of Crohn's disease: A retrospective cohort study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

78 authors at 4 institutions in 2 countries.

Valerio CelentanoPortsmouth Hospitals NHS Trust, Portsmouth, UK. valeriocelentano@yahoo.it.ORCID http://orcid.org/0000-0002-3562-9082
Gianluca PellinoDepartment of Advanced Medical and Surgical Science, Universita' degli Studi della Campania Luigi Vanvitelli, Naples, Italy.
Antonino SpinelliColon and Rectal Surgery Unit, Humanitas Clinical and Research Center, Rozzano, Italy.
Francesco SelvaggiDepartment of Advanced Medical and Surgical Science, Universita' degli Studi della Campania Luigi Vanvitelli, Naples, Italy.
SICCR Current status of Crohn’s disease surgery collaborative
Valerio Celentano
Gianluca Pellino
Matteo Rottoli
Gilberto Poggioli
Giuseppe Sica
Mariano Cesare Giglio
Michela Campanelli
Claudio Coco
Gianluca Rizzo
Francesco Sionne
Francesco Colombo
Gianluca Sampietro
Giulia Lamperti
Diego Foschi
Ferdinando Ficari
Ludovica Vacca
Marta Cricchio
Francesco Giudici
Lucio Selvaggi
Guido Sciaudone
Roberto Peltrini
Andrea Manfreda
Luigi Bucci
Raffaele Galleano
Omar Ghazouani
Luigi Zorcolo
Simona Deidda
Angelo Restivo
Andrea Braini
Francesca Di Candido
Matteo Sacchi
Michele Carvello
Stefania Martorana
Giovanni Bordignon
Imerio Angriman
Angela Variola
Mirko Di Ruscio
Giuliano Barugola
Andrea Geccherle
Francesca Paola Tropeano
Gaetano Luglio
Marta Tanzanu
Diego Sasia
Marco Migliore
Maria Carmela Giuffrida
Enrico Marrano
Gianluigi Moretto
Harmony Impellizzeri
Gaetano Gallo
Giuseppina Vescio
Giuseppe Sammarco
Giovanni Terrosu
Giacomo Calini
Andrea Bondurri
Anna Maffioli
Gloria Zaffaroni
Andrea Resegotti
Massimiliano Mistrangelo
Marco Ettore Allaix
Fiorenzo Botti
Matteo Prati
Luigi Boni
Serena Perotti
Michela Mineccia
Antonio Giuliani
Lucia Romano
Giorgio Maria Paolo Graziano
Luigi Pugliese
Andrea Pietrabissa
GianGaetano Delaini
Antonino Spinelli
Francesco Selvaggi
, on behalf of the Italian Society of Colorectal Surgery SICCR
University of Campania "Luigi Vanvitelli" · ITHumanitas University · ITImperial College London · GBPortsmouth Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A limited ileocaecal resection is the most frequently performed procedure for ileocaecal CD and different anastomotic configurations and techniques have been described. This manuscript audited the different anastomotic techniques used in a national study and evaluated their influence on postoperative outcomes following ileocaecal resection for primary CD. This is a retrospective, multicentre, observational study promoted by the Italian Society of Colorectal Surgery (SICCR), including all adults undergoing elective ileocaecal resection for primary CD from June 2018 May 2019. Postoperative morbidity within 30 days of surgery was the primary endpoint. Postoperative length of hospital stay (LOS) and anastomotic leak rate were the secondary outcomes. 427 patients were included. The side to side anastomosis was the chosen configuration in 380 patients (89%). The stapled anastomotic (n = 286; 67%), techniques were preferred to hand-sewn (n = 141; 33%). Postoperative morbidity was 20.3% and anastomotic leak 3.7%. Anastomotic leak was independent of the type of anastomosis performed, while was associated with an ASA grade ≥ 3, presence of perianal disease and ileocolonic localization of disease. Four predictors of LOS were identified after multivariate analysis. The laparoscopic approach was the only associated with a reduced LOS (p = 0.017), while age, ASA grade ≥ 3 or administration of preoperative TPN were associated with increased LOS. The side to side was the most commonly used anastomotic configuration for ileocolic reconstruction following primary CD resection. There was no difference in postoperative morbidity according to anastomotic technique and configuration. Anastomotic leak was associated with ASA grade ≥ 3, a penetrating phenotype of disease and ileo-colonic distribution of CD.

Indexed as

AdolescentAdultAgedAged, 80 and overAnastomosis, SurgicalAnastomotic LeakCecumCrohn DiseaseDigestive System Surgical ProceduresElective Surgical ProceduresFemaleHumansIleumLaparoscopyLength of StayMaleColorectal surgeryCrohn’s diseaseIleocaecal resectionInflammatory bowel diseaseNational audit

Identifiers

PMID33409848
OpenAlexW3118619268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.