SynthesisEuropean radiology2021
The prognostic value of late gadolinium enhancement in heart diseases: an umbrella review of meta-analyses of observational studies.
Synthesis in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Diagnostic accuracy of late iodine enhancement on cardiac CT for myocardial tissue characterization: a systematic review and meta-analysis.European radiology · 2025Pooled it
- The prognostic value of myocardial salvage index by cardiac magnetic resonance in ST-segment elevation myocardial infarction patients: a systematic review and meta-analysis.European radiology · 2023Pooled it
- Global burden of mental health problems among children and adolescents during COVID-19 pandemic: An umbrella review.Psychiatry research · 2022Pooled it
- Correlation between cardiac and hepatic native T1 value and myocardial late gadolinium enhancement in children with Kawasaki disease.Quantitative imaging in medicine and surgery · 2025Article
- Late/delayed gadolinium enhancement in MRI after intravenous administration of extracellular gadolinium-based contrast agents: is it worth waiting?Magma (New York, N.Y.) · 2024Review
- Impact of Cardiac Magnetic Resonance on the Diagnosis of Left Ventricular Noncompaction-A 15-Year Experience.Journal of clinical medicine · 2024Article
- Value of a short non-contrast CMR protocol in MINOCA.European radiology · 2024Article
- Myocardial Late Gadolinium Enhancement (LGE) in Cardiac Magnetic Resonance Imaging (CMR)-An Important Risk Marker for Cardiac Disease.Journal of cardiovascular development and disease · 2024Review
- Prediction of left ventricular ejection fraction improvement in patients with ischemic cardiomyopathy after coronary artery bypass grafting based on cardiac magnetic resonance.Cardiovascular diagnosis and therapy · 2023Article
- Myocardial infarct size for predicting improvements in cardiac function in patients with ischemic cardiomyopathy following coronary artery bypass grafting.Quantitative imaging in medicine and surgery · 2023Article
- Multimodality imaging in cardio-oncology: the added value of CMR and CCTA.The British journal of radiology · 2023Review
- Heart age gap estimated by explainable advanced electrocardiography is associated with cardiovascular risk factors and survival.European heart journal. Digital health · 2023Article
- An overview of meta-analyses on radiomics: more evidence is needed to support clinical translation.Insights into imaging · 2023Article
- Cardiovascular magnetic resonance findings in Danon disease: a case series of a family.Frontiers in cardiovascular medicine · 2023Article
- An updated systematic review of radiomics in osteosarcoma: utilizing CLAIM to adapt the increasing trend of deep learning application in radiomics.Insights into imaging · 2022Article
- A systematic review of radiomics in pancreatitis: applying the evidence level rating tool for promoting clinical transferability.Insights into imaging · 2022Article
- Novel Cardiac Computed Tomography Methods for the Assessment of Anthracycline Induced Cardiotoxicity.Frontiers in cardiovascular medicine · 2022Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesCardiac magnetic resonance imaging (CMR) has proven itself as an accurate and robust diagnostic approach and has been widely used in the detection of various heart diseases. An increasing number of studies focusing more on the prognostic aspect of LGE-CMR arose in recent years, contributing to the redundant systematic reviews and meta-analyses in this field. By providing a bird's eye view and performing scrupulous evidence rating, this umbrella review aims to help clinical practitioners and policy-makers interpret the results of the meta-analyses on the prognostic role of late gadolinium enhancement (LGE) in patients with heart diseases.
methodsAn umbrella review of meta-analyses of observational studies.
resultsThe 11 included systematic reviews comprise 33 meta-analyses covering 11 types of heart diseases, 19 different outcomes, 23,058 subjects, and 5393 events. Thirty-one of 33 meta-analyses were found supported by weak pieces of evidence and the remaining were deemed not suggestive. The meta-analysis with a p value of 9.21 × 10
conclusionsThe prognostic role of LGE in DCM patients in terms of MACE is supported by highly suggestive evidence, which may facilitate the optimization of the timing of prophylactic implantable or wearable implantable cardioverter-defibrillators (ICD) considering the high risk of MACE and lower expectation of recovery. KEY POINTS: • Cardiac magnetic resonance imaging (CMR) has been widely used in the detection of various heart diseases. Numerous studies focusing on the prognostic aspect of LGE arose in recent years. • The meta-analysis on the prognostic role of LGE in dilated cardiomyopathy (DCM) patients in terms of major adverse cardiovascular events (MACE) by Becker et al was updated and was deemed to be supported by highly suggestive evidence. • The credibility of the meta-analysis supported by highly suggestive evidence may facilitate the optimization of the timing of prophylactic implantable or wearable implantable cardioverter defibrillators (ICD) considering the high risk of MACE and lower expectation of recovery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.