SynthesisEuropean radiology2021
Diagnostic performance and interobserver agreement of the callosal angle and Evans' index in idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis.
Synthesis in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- The effect of magnetic interference by magnetic resonance imaging on programmable shunt valves in patients with normal pressure hydrocephalus: a systematic review and pooled analysis.Fluids and barriers of the CNS · 2026Pooled it
- Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis.Acta neurochirurgica · 2023Pooled it
- Evans' Index and Frontal and Occipital Horn Ratio in Correlation to Volumetric Data of Lateral Ventricles in a Population-based MRI Study.Clinical neuroradiology · 2026Article
- Moving on in hydrocephalus imaging: from 2D to 3D biomarkers.Acta neurochirurgica · 2026Review
- Screening for Normal Pressure Hydrocephalus on Head CT Using Automated Callosal Angle Assessment.Tomography (Ann Arbor, Mich.) · 2026Article
- Fully Automated Deep Learning-Based Pipeline for Evans Index Measurement from Raw 3D MRI.Neuroscience informatics · 2026Article
- Fully Automated Deep Learning-Based Pipeline for Evans Index Measurement from Raw 3D MRI.medRxiv : the preprint server for health sciences · 2025Article
- Implications of the glymphatic system in the diagnostic and surgical workup of normal pressure hydrocephalus.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Diagnostic performance of black tent sign on 3D T2 SPACE in the diagnosis of idiopathic normal-pressure hydrocephalus.Japanese journal of radiology · 2025Article
- Automated Idiopathic Normal Pressure Hydrocephalus Diagnosis via Artificial Intelligence-Based 3D T1 MRI Volumetric Analysis.AJNR. American journal of neuroradiology · 2025Article
- Automated Detection of Normal Pressure Hydrocephalus Using CT Imaging for Calculating the Ventricle-to-Subarachnoid Volume Ratio.AJNR. American journal of neuroradiology · 2025Article
- A case of idiopathic normal pressure hydrocephalus without enlarged ventricle and with negative tap test.Surgical neurology international · 2025Article
- A review of applications of automated ventricular parcellation from magnetic resonance imaging of the brain.Frontiers in neurology · 2025Review
- The benefits of ventriculoperitoneal shunting in normal pressure hydrocephalus patients-a follow-up of three years.Acta neurochirurgica · 2024Article
- Brain and Ventricle Volume Alterations in Idiopathic Normal Pressure Hydrocephalus Determined by Artificial Intelligence-Based MRI Volumetry.Diagnostics (Basel, Switzerland) · 2024Article
- Improve the diagnosis of idiopathic normal pressure hydrocephalus by combining abnormal cortical thickness and ventricular morphometry.Frontiers in aging neuroscience · 2024Article
- A Male Patient with Hydrocephalus via Multimodality Diagnostic Approaches: A Case Report.Cyborg and bionic systems (Washington, D.C.) · 2024Article
- Awareness level of idiopathic normal pressure hydrocephalus among health-care providers.Surgical neurology international · 2024Article
- Brain blood flow pulse analysis may help to recognize individuals who suffer from hydrocephalus.Acta neurochirurgica · 2023Article
- Idiopathic Normal Pressure Hydrocephalus: The Real Social and Economic Burden of a Possibly Enormous Underdiagnosis Problem.Tomography (Ann Arbor, Mich.) · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the diagnostic performance and interobserver agreement of the callosal angle and Evans' index in idiopathic normal pressure hydrocephalus (iNPH).
methodsA systematic search of MEDLINE and EMBASE was performed to find studies assessing the diagnostic performance or interobserver agreement of the callosal angle and Evans' index in iNPH. Pooled sensitivity and specificity of the two radiologic indices were calculated. The area under the curve (AUC) was obtained based on a hierarchical summary receiver operating characteristic curve. The diagnostic performances of both radiologic indices were compared in subgroup analysis. To evaluate interobserver agreement, the pooled correlation coefficient was calculated.
resultsTen original articles (874 patients) were included. The pooled sensitivity and specificity of the callosal angle in the diagnosis of iNPH were 91% (95% CI, 86-94%) and 93% (95% CI, 89-96%), respectively. The pooled sensitivity and specificity of Evans' index were 96% (95% CI, 47-100%) and 83% (95% CI, 77-88%), respectively. Subgroup analysis demonstrated a significant higher specificity of the callosal angle than that of Evans' index (p < 0.01). The AUC of the callosal angle and Evans' index were 0.97 (95% CI, 0.95-0.98) and 0.87 (95% CI, 0.84-0.90), respectively. The pooled correlation coefficients for the callosal angle and Evans' index were 0.92 (95% CI, 0.82-0.96) and 0.92 (95% CI, 0.83-0.97), respectively.
conclusionsOur meta-analysis demonstrated a high performance of the callosal angle in the diagnosis of iNPH. Evans' index showed reasonable diagnostic performance with high sensitivity but low specificity. Interobserver agreements were excellent in both radiologic indices. KEY POINTS: • Callosal angle showed high diagnostic performance in idiopathic normal pressure hydrocephalus. • Evans' index showed reasonable diagnostic performance with high sensitivity but low specificity. • Interobserver agreements were excellent in both callosal angle and Evans' index.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.