SynthesisClinical oral investigations2021
Prevalence of temporomandibular joint disorders: a systematic review and meta-analysis.
Synthesis in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06602375 (The Effect of Manual Physical Therapy and Exercise in Addition to Routine Dental Care in Individuals With Temporomandibular Disorders), which is not on this map. Cited by 411 papers, 19 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Manual Physical Therapy and Exercise in Addition to Routine Dental Care in Individuals With Temporomandibular Disorders: a Randomized Controlled Trial
Who cites it
411 citing papers in PubMed, 19 syntheses or guidelines pooled it, 794 citations in OpenAlex.
- Heart rate variability after hospital discharge in perinatal risk populations: a systematic review and meta-analysis.Pediatric research · 2026Pooled it
- The Efficacy of Extracorporeal Shock Wave Therapy for Temporomandibular Joint Disorders: A Meta-Analysis.Journal of oral rehabilitation · 2026Pooled it
- Efficacy of manual therapy by different healthcare professionals on pain and function in temporomandibular disorders: a systematic review of randomized controlled trials.The Journal of manual & manipulative therapy · 2026Pooled it
- Efficacy of Myofascial Release Therapy and Related Soft-Tissue Techniques for Pain in Temporomandibular Disorders: A Systematic Review of Randomized Controlled Trials.Journal of oral rehabilitation · 2026Pooled it
- Efficacy and Safety of Intra-Articular Therapies for Temporomandibular Disorders: A Systematic Review and Meta-Analysis.Oral diseases · 2026Pooled it
- Comparative effectiveness of nonpharmacological therapies for adult myogenic temporomandibular disorders: a network meta-analysis of randomized trials.BMC oral health · 2026Pooled it
- Temporomandibular joint disorders in dental students - a systematic review of the literature.BMC oral health · 2026Pooled it
- Endocrine diseases in Brazilian small-animal hospitals and referral caseloads: A systematic review and meta-analysis of proportions.Open veterinary journal · 2026Pooled it
- Temporomandibular joint disorders and tinnitus: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Prevalence of cognitive frailty, reversible and potentially reversible cognitive frailty among older adults without dementia: a systematic review and meta-analysis.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Pooled it
- Effectiveness of treatments for temporomandibular joint osteoarthritis: a systematic review and meta-analysis.Clinical oral investigations · 2025Pooled it
- Intra-articular injections in temporomandibular arthralgia: a systematic review.Oral and maxillofacial surgery · 2025Pooled it
- Efficacy of duloxetine in treating temporomandibular joint disorder: a systematic review with bayesian meta-analysis.BMC oral health · 2025Pooled it
- Trends in the Prevalence and Development of Alzheimer's Disease Among the Elderly Chinese Population: A Systematic Review.Revista de neurologia · 2025Pooled it
- Efficacy of intra-articular opioid injections for managing temporomandibular joint nociception: a systematic review.Pain management · 2025Pooled it
- The Safety and Efficacy of Glucosamine and/or Chondroitin in Humans: A Systematic Review.Nutrients · 2025Pooled it
- The relationship between psychological factors and temporomandibular disorders: a systematic review and meta-analysis.Head & face medicine · 2025Pooled it
- Global prevalence of temporomandibular disorders: a systematic review and meta-analysis.Journal of oral & facial pain and headache · 2025Pooled it
- Temporomandibular disorder prevalence in malocclusion patients: a meta-analysis.Head & face medicine · 2025Pooled it
- Injection of Adipose-Derived Mesenchymal Stem Cell-Enriched Adipose Extract for Temporomandibular Joint Osteoarthritis: A Randomised Controlled Trial.International dental journal · 2026Trial
351 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
objectivesThe aim of this systematic review was to evaluate the prevalence of temporomandibular joint disorders (TMJD) among the general population. MATERIALS AND
methodsFive main electronic databases and three grey literature were searched to identify observational studies in which TMJD was diagnosed using the research diagnostic criteria (RDC/TMD) or diagnostic criteria (DC/TMD). The studies were blindly selected by two reviewers based on eligibility criteria. Risk of bias (RoB) was assessed using the Joanna Briggs Institute Critical Appraisal Checklist, and the "R" Statistics software was used to perform meta-analyses.
resultsFrom 2741 articles, 21 were included. Ten studies were judged at low RoB, seven at moderate, and four at high. The TMJD investigated were as follows: arthralgia, disk displacement (DDs) with reduction (DDwR), DDwR with intermittent locking, DDs without reduction (DDwoR) with limited opening, DDwoR without limited opening, degenerative joint disease (DJD), osteoarthritis, osteoarthrosis, and subluxation. The main results from prevalence overall meta-analyses for adults/elderly are as follows: TMJD (31.1%), DDs (19.1%), and DJD (9.8%). Furthermore, for children/adolescents are as follows: TMJD (11.3%), DDs (8.3%), and DJD (0.4%). Considering the individual diagnosis meta-analyses, the most prevalent TMJD is DDwR for adults/elderly (25.9%) and children/adolescents (7.4%).
conclusionsThe overall prevalence of TMJD was approximately 31% for adults/elderly and 11% for children/adolescents, and the most prevalent TMJD was DDwR. CLINICAL RELEVANCE: Knowledge about the frequency of TMJD can encourage dentists to consider appropriate strategies for early and correct diagnosis and, if need be, correct management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.