Evidence map›Paper›PMID 33409650›Full record

ReviewCell and tissue research2021

Odor coding in the mammalian olfactory epithelium.

Smija M Kurian, Rafaella G Naressi, Diogo Manoel, Ann-Sophie Barwich, Bettina Malnic, Luis R Saraiva

Open access · hybridAbstract readReview
In one paragraph

Review in Cell and tissue research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Neurophysiological Responses to Inhalation ofPlants (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. [Application of optogenetic technology in the research on olfactory bulb neural projection from advanced brain regions to regulate olfactory signal processing].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Connectomics of theeLife · 2023
    Article
  16. Olfactory Function and Olfactory Disorders.Laryngo- rhino- otologie · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Smija M KurianSidra Medicine, Doha, Qatar.
Rafaella G NaressiDepartment of Biochemistry, University of São Paulo, São Paulo, Brazil.
Diogo ManoelSidra Medicine, Doha, Qatar.
Ann-Sophie BarwichIndiana University, Bloomington, IN, USA. abarwich@iu.edu.
Bettina MalnicDepartment of Biochemistry, University of São Paulo, São Paulo, Brazil. bmalnic@iq.usp.br.
Luis R SaraivaSidra Medicine, Doha, Qatar. saraivalmr@gmail.com.ORCID http://orcid.org/0000-0003-4079-0396
Universidade de São Paulo · BRIndiana University Bloomington · USQatar Airways (Qatar) · QA

Funding

Qatar National Research Fund JSREP07-016-1-006
6 · The paper itself

Abstract

Noses are extremely sophisticated chemical detectors allowing animals to use scents to interpret and navigate their environments. Odor detection starts with the activation of odorant receptors (ORs), expressed in mature olfactory sensory neurons (OSNs) populating the olfactory mucosa. Different odorants, or different concentrations of the same odorant, activate unique ensembles of ORs. This mechanism of combinatorial receptor coding provided a possible explanation as to why different odorants are perceived as having distinct odors. Aided by new technologies, several recent studies have found that antagonist interactions also play an important role in the formation of the combinatorial receptor code. These findings mark the start of a new era in the study of odorant-receptor interactions and add a new level of complexity to odor coding in mammals.

Indexed as

OdorantsAnimalsMammalsOlfactory Receptor NeuronsAntagonistCombinatorial codeOdorantOdor codingOlfactionReceptorSmell

Identifiers

PMID33409650
PMCPMC7873010
OpenAlexW3118566525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.