Evidence map›Paper›PMID 33409493›Full record

ArticleBrain communications2020

Lateralized memory circuit dropout in Alzheimer's disease patients.

Ashley Tyrer, Jessica R Gilbert, Sarah Adams, Alexandra B Stiles, Azziza O Bankole, Iain D Gilchrist, Rosalyn J Moran

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Ashley TyrerDepartment of Engineering Mathematics, University of Bristol, Bristol BS8 1UB, UK.ORCID 0000-0002-6411-8345
Jessica R GilbertNational Institute for Mental Health, Bethesda, MD 20892, USA.ORCID 0000-0002-4194-6172
Sarah AdamsSchool of Medicine, University of Virginia, Charlottesville, VA 22904, USA.
Alexandra B StilesCollege of Medicine, Ohio State University, Columbus, OH 43210, USA.
Azziza O BankoleDepartment of Psychiatry and Behavioural Medicine, Virginia Tech Carilion School of Medicine, Roanoke, VA 24016, USA.
Iain D GilchristSchool of Psychological Science, University of Bristol, Bristol BS8 1TU, UK.
Rosalyn J MoranDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 8AF, UK.
University of Bristol · GBCarilion Clinic · USKing's College London · GBNational Institute of Mental Health · USThe Ohio State University · USUniversity of Virginia · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

Altered connectivity within neuronal networks is often observed in Alzheimer's disease. However, delineating pro-cognitive compensatory changes from pathological network decline relies on characterizing network and task effects together. In this study, we interrogated the dynamics of occipito-temporo-frontal brain networks responsible for implicit and explicit memory processes using high-density EEG and dynamic causal modelling. We examined source-localized network activity from patients with Alzheimer's disease (

Indexed as

Alzheimer’s diseasecomputational psychiatryEEGexecutive functionmemory

Identifiers

PMID33409493
PMCPMC7772115
OpenAlexW3111695397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.