Evidence map›Paper›PMID 33409387›Full record

ArticleHeliyon2020

SialoPen peptides are new cationic foldamers with remarkable cell permeability.

I Abrrey Monreal, Erik M Contreras, Gary A Wayman, Hector C Aguilar, Jonel P Saludes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

I Abrrey MonrealImmunology and Microbiology Department, Cornell University, Ithaca, NY 14850, USA.
Erik M ContrerasImmunology and Microbiology Department, Cornell University, Ithaca, NY 14850, USA.
Gary A WaymanDepartment of Integrative Physiology and Neuroscience, Washington State University, Pullman, WA 99164, USA.
Hector C AguilarImmunology and Microbiology Department, Cornell University, Ithaca, NY 14850, USA.
Jonel P SaludesDepartment of Chemistry, Washington State University, Pullman, WA 99164, USA.
Cornell University · USUniversity of San Agustin · PHWashington State University · US

Funding

Mechanisms of Nipah virus fusion and entryR01AI109022 · NIAID · WASHINGTON STATE UNIVERSITY · PI AGUILAR-CARRENO, HECTOR · 2014 to 2024
$4.3M
Leptin regulation of GABAergic synaptogenesis and excitation-inhibition balance during development: effects of maternal obesityR01HD092369 · NICHD · WASHINGTON STATE UNIVERSITY · PI WAYMAN, GARY ALLEN · 2018 to 2022
$2.0M
AQUISITION OF A 600 MHZ NMR SPECTROMETERS10RR012948 · NCRR · WASHINGTON STATE UNIVERSITY · PI EVANS, JEREMY N · 1998 to 1998
–
NCRR NIH HHS S10 RR012948NIAID NIH HHS R01 AI109022NICHD NIH HHS R01 HD092369
6 · The paper itself

Abstract

The ability to access intracellular targets is of vital importance as the number of identified druggable intracellular targets increases every year. However, intracellular delivery poses a formidable barrier, as many potential therapeutics are impermeable to cell membranes, which hinders their practical application in drug development. Herein we present

Indexed as

Biological sciencesCargo transportCell penetrating peptidesDrug deliveryFoldamerHealth sciencesHelicalInfectious diseaseNeuron translocationPolymerPublic healthSialic acidSPPSUnnatural amino acidVirology

Identifiers

PMID33409387
PMCPMC7773882
OpenAlexW3114079993

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.