Evidence map›Paper›PMID 33409365›Full record

ArticleJournal of dental anesthesia and pain medicine2020

Intraosseous anesthesia in symptomatic irreversible pulpitis: Impact of bone thickness on perception and duration of pain.

Manfred Nilius, Charlotte Mueller, Minou Helene Nilius, Dominik Haim, Henry Leonhardt, Guenter Lauer

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of dental anesthesia and pain medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Expert consensus on digital guided therapy for endodontic diseases.International journal of oral science · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Manfred NiliusNiliusklinik, Londoner Bogen 6, D-44269 Dortmund, Germany.ORCID https://orcid.org/0000-0003-0297-4012
Charlotte MuellerNiliusklinik, Londoner Bogen 6, D-44269 Dortmund, Germany.ORCID https://orcid.org/0000-0001-7581-2896
Minou Helene NiliusNiliusklinik, Londoner Bogen 6, D-44269 Dortmund, Germany.ORCID https://orcid.org/0000-0003-4789-7882
Dominik HaimTechnische Universität Dresden, University Hospital "Carl Gustav Carus", Department of Oral and Maxillofacial Surgery, Dresden, Germany.ORCID https://orcid.org/0000-0002-5299-3468
Henry LeonhardtTechnische Universität Dresden, University Hospital "Carl Gustav Carus", Department of Oral and Maxillofacial Surgery, Dresden, Germany.ORCID https://orcid.org/0000-0003-1412-0276
Guenter LauerTechnische Universität Dresden, University Hospital "Carl Gustav Carus", Department of Oral and Maxillofacial Surgery, Dresden, Germany.ORCID https://orcid.org/0000-0001-7536-0885
University Hospital Carl Gustav Carus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntraosseous anesthesia (IO) allows the anesthetic solution to be injected directly into the cancellous bone. The anesthetic solution immediately reaches the periapical region, and thus the axonal area of the nerve, where it can temporarily disable the sodium pump. The effect is felt almost without any time delay, and only a small amount of anesthetic solution is required.

methodsThis study aims to investigate the efficacy of IO using the Anesto® device after infiltration anesthesia (IA) and/or inferior alveolar nerve block anesthesia (IANB) failed to work in symptomatic irreversible pulpitis (hot tooth). The 33 patients included in the study were treated additionally with 1.7 ml articaine hydrochloride with 1:100,000 epinephrine hydrochloride (Ultracain® D-S, Sanofi-Aventis, Frankfurt, Germany) IO.

resultsThe electrical pulp test showed that 95.76% of the volunteers reacted positively to the combination of IANB or IA with the IO. In women, the additive IO was effective at 97.22%. In men, the IO led to pain elimination in 94.00% of cases. The duration of the IO was less than a quarter of an hour (13.03 min). The IO worked longer in women than in men (13.61 min vs. 12.33 min). Overall, more than every third tooth that needed trepanation was located in the posterior area of the mandible (36.4%). Treatment of hot teeth in this area was associated with an increased pulse rate and increased residual pain. There was a moderate correlation (Spearman-Rho [IRI] = 0.280) between the Visual Analog Scale (VAS) score and bone density, and a significant correlation (IRI = 0.612) between subjective residual pain and bone width. The IO resulted in a moderate, transient increase in the pulse rate by approximately 20 bpm. This is similar to the temporary increase in heart rate after conventional anesthesia techniques in non-preloaded patients and can be considered clinically irrelevant.

conclusionIO with the Anesto® device as an extension and deepening of local pain elimination is recommended for the treatment of hot teeth.

Indexed as

Anesto® deviceHot toothIntraosseous AnesthesiaIrreversible PulpitisLocal Anesthesia

Identifiers

PMID33409365
PMCPMC7783377
OpenAlexW3113483524

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.