ArticleOpen forum infectious diseases2020
Isolated Cerebral Mucormycosis in Immunocompetent Adults who Inject Drugs: Case Reports and Systematic Review of the Literature.
Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Isolated Cerebral Mucormycosis Mimicking Meningioma in an Uncontrolled Diabetic Patient: A Case Report.Clinical case reports · 2026Article
- Yeast fungaemia among injection drug users in France (2012-2022): a cross-sectional observational study.The Lancet regional health. Europe · 2025Article
- Fungal Infections in People Who Use Drugs.Open forum infectious diseases · 2025Review
- Immunocompetent isolated cerebral mucormycosis presenting with obstructive hydrocephalus: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Intracranial Cavernous Malformation with Concomitant Isolated Cerebral Mucormycosis Infection: A Case Report.Asian journal of neurosurgery · 2024Article
- Social determinants of health as drivers of fungal disease.EClinicalMedicine · 2023Review
- Epidemiology, Modern Diagnostics, and the Management of Mucorales Infections.Journal of fungi (Basel, Switzerland) · 2023Review
- Isolated cerebral mucormycosis that looks like stroke and brain abscess: A case report and review of the literature.World journal of clinical cases · 2023Article
- Isolated cerebral mucormycosis: A case discussion.IDCases · 2023Article
- Development of a Monoclonal Antibody and a Serodiagnostic Lateral-Flow Device Specific toJournal of fungi (Basel, Switzerland) · 2022Article
- Isolated Cerebral Mucormycosis Caused byDiagnostics (Basel, Switzerland) · 2022Article
- Case Report: Metagenomics Next-Generation Sequencing for Diagnosing Cerebral Infarction and Infection Caused by Hematogenous Disseminated Mucormycosis in a Patient With Acute Lymphoblastic Leukemia.Frontiers in medicine · 2021Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMucormycosis involves life-threatening rapidly progressive angioinvasion with infiltration across tissue planes, resulting in necrosis and thrombosis, most commonly seen in the setting of immunocompromised states. We describe 2 cases of isolated cerebral mucormycosis in immunocompetent adults and describe this syndrome in detail in the context of a systemic literature review.
methodsUsing the criteria (1) isolated cerebral disease, (2) mucormycosis (by polymerase chain reaction, culture, or pathology), and (3) affected an immunocompetent individual, we identified 53 additional cases from 1969 to 2020.
resultsOf these 55 cases, ~60% occurred in men, >70% were in patients under age 35, 92% were associated with intravenous drug use, and >85% had infection centered in the basal ganglia. Many presented with cranial nerve deficits, headache, focal weakness, or altered mental status.
conclusionsNo patient survived without amphotericin, and steroid administration was associated with worse outcomes. Given the current opioid crisis, this syndrome may be seen more frequently.
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