ArticleBiomedical optics express2020
Three-dimensional label-free imaging and quantification of migrating cells during wound healing.
Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Optical diffraction tomographic microscopy: a cutting-edge label-free three-dimensional bioimaging.Biophysics reports · 2026Article
- Article
- A Comprehensive Review of Optical Metrology and Perception Technologies.Sensors (Basel, Switzerland) · 2025Review
- Volumetric segmentation of biological cells and subcellular structures for optical diffraction tomography images.Biomedical optics express · 2023Article
- Numerical refractive index correction for the stitching procedure in tomographic quantitative phase imaging.Biomedical optics express · 2022Article
- Review
- Advances in Digital Holographic Interferometry.Journal of imaging · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The wound-healing assay is a simple but effective tool for studying collective cell migration (CCM) that is widely used in biophysical studies and high-throughput screening. However, conventional imaging and analysis methods only address two-dimensional (2D) properties in a wound healing assay, such as gap closure rate. This is unfortunate because biological cells are complex 3D structures, and their dynamics provide significant information about cell physiology. Here, we presented 3D label-free imaging for wound healing assays and investigated the 3D dynamics of CCM using optical diffraction tomography. High-resolution subcellular structures as well as their collective dynamics were imaged and analyzed quantitatively.
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Registered trials
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