Evidence map›Paper›PMID 33408897›Full record

ArticleJournal of pharmacopuncture2020

Cytotoxic Effect of Bee (

Sima Khalilifard Borojeni, Hossein Zolfagharian, Mahdi Babaie, Iraj Javadi

Open access · diamondAbstract read
In one paragraph

Article in Journal of pharmacopuncture, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Therapeutic Bioactivity Exerted by theMolecules (Basel, Switzerland) · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Intrinsic apoptotic effect of Anatolian honeybee (Turkish journal of biology = Turk biyoloji dergisi · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Pharmacological Screening of Venoms from Five BrazilianInternational journal of molecular sciences · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sima Khalilifard BorojeniDepartment of Venomous Animals and Antivenom Production, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.ORCID https://orcid.org/0000-0002-0010-9896
Hossein ZolfagharianDepartment of Venomous Animals and Antivenom Production, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.ORCID https://orcid.org/0000-0002-8093-2400
Mahdi BabaieDepartment of Venomous Animals and Antivenom Production, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.ORCID https://orcid.org/0000-0001-8366-5929
Iraj JavadiDepartment of Toxicology, Islamic Azad University, Shahreza Branch, Shahreza, Isfahan, Iran.ORCID https://orcid.org/0000-0001-8635-1554
Razi Vaccine and Serum Research Institute · IRIslamic Azad University of Shahreza · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesNowadays cancer treatment is an important challenge in the medical world that needs better therapies. Many active secretions produced by insects such as honey bees used to discover new anticancer drugs. Bee venom (BV) has a potent anti inflammatory, anti cancer and tumor effects. The aim of present study is evaluation of anticancer effects induced by

methodsAmV was selected for study on cancer cell lines. Total protein, molecular weight and LD

resultsThe results from MTT assay showed that 3.125 µg/mL of A

conclusionThe data showed that using lower dosage of AmV during treatment period cause inhibition of proliferation in time and dose dependant manner. Findings indicated that some ingredients of AmV have anticancer effects and with further investigation it can be used in production of anticancer drugs.

Indexed as

apoptosisbee venomcancercell linesMTT

Identifiers

PMID33408897
PMCPMC7772077
OpenAlexW3113540224

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.