Evidence map›Paper›PMID 33408891›Full record

ArticleJournal of breast cancer2020

Whole Exome Sequencing in the Male Breast Cancer with Prolactinoma: A Case Report and Literature Review.

Shuai Hao, Miao Huang, Wuguo Tian, Yi Chen, Jianjie Zhao, Donglin Luo

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of breast cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shuai HaoDepartment of Breast, Thyroid Surgery, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0003-4942-2215
Miao HuangNursing School, Chongqing Medical University, Chongqing, China.ORCID 0000-0001-6828-8678
Wuguo TianDepartment of Breast, Thyroid Surgery, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0001-6414-6808
Yi ChenDepartment of Breast, Thyroid Surgery, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0002-6919-5446
Jianjie ZhaoDepartment of Breast, Thyroid Surgery, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0003-0950-9623
Donglin LuoDepartment of Breast, Thyroid Surgery, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0001-9329-0147
Army Medical University · CNChongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male breast cancer (MBC) is rare and accounts for approximately 1% of all breast cancer cases worldwide. Previous studies have suggested that several factors significantly increase the risk of MBC. Prolactinoma has the highest incidence rate among patients with functional pituitary tumors. However, whether prolactinoma is involved in the onset and progression of breast cancer remains unclear. To date, there are only five case reports globally on MBC with concurrent prolactinoma. We hereby describe the first case of MBC with prolactinoma in China. We also explored the patient's genetic profile using whole exome sequencing. Our findings may help advance our understanding of the molecular pathogenesis of MBC. Further molecular analyses of such cases are warranted to improve auxiliary molecular diagnostic methods and targeted therapy for MBC.

Indexed as

Breast neoplasms, malePituitary neoplasmsProlactinomaWhole exome sequencing

Identifiers

PMID33408891
PMCPMC7779730
OpenAlexW3112430679

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.