Evidence map›Paper›PMID 33408795›Full record

ArticleTheranostics2021

Integrated photodynamic Raman theranostic system for cancer diagnosis, treatment, and post-treatment molecular monitoring.

Conor C Horgan, Mads S Bergholt, Anika Nagelkerke, May Zaw Thin, Isaac J Pence, Ulrike Kauscher, Tammy L Kalber, Daniel J Stuckey, Molly M Stevens

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Conor C HorganDepartment of Materials, Imperial College London, London SW7 2AZ, UK.
Mads S BergholtDepartment of Materials, Imperial College London, London SW7 2AZ, UK.
Anika NagelkerkeDepartment of Materials, Imperial College London, London SW7 2AZ, UK.
May Zaw ThinCentre for Advanced Biomedical Imaging, University College London, London WC1E 6DD, UK.
Isaac J PenceDepartment of Materials, Imperial College London, London SW7 2AZ, UK.
Ulrike KauscherDepartment of Materials, Imperial College London, London SW7 2AZ, UK.
Tammy L KalberCentre for Advanced Biomedical Imaging, University College London, London WC1E 6DD, UK.
Daniel J StuckeyCentre for Advanced Biomedical Imaging, University College London, London WC1E 6DD, UK.
Molly M StevensDepartment of Materials, Imperial College London, London SW7 2AZ, UK.
NIHR Imperial Biomedical Research Centre · GBUniversity College London · GBImperial College London · GB

Funding

British Heart Foundation FS/15/33/31608Medical Research Council MR/R026416/1Wellcome Trust
6 · The paper itself

Abstract

Theranostics, the combination of diagnosis and therapy, has long held promise as a means to achieving personalised precision cancer treatments. However, despite its potential, theranostics has yet to realise significant clinical translation, largely due the complexity and overriding toxicity concerns of existing theranostic nanoparticle strategies.

Indexed as

Theranostic NanomedicineAnimalsApoptosisCell ProliferationColorectal NeoplasmsDrug MonitoringFemaleHumansMiceMice, NudePhotochemotherapyPhotosensitizing AgentsSpectrum Analysis, RamanTumor Cells, CulturedXenograft Model Antitumor AssaysPhotosensitizing AgentsCancerNanoparticle-FreePhotodynamic TherapyRaman SpectroscopyTheranostics

Identifiers

PMID33408795
PMCPMC7778600
OpenAlexW3112806278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.