Evidence map›Paper›PMID 33408751›Full record

ArticleDrugs in context2020

Symptomatic uncomplicated diverticular disease management: an innovative food-grade formulation of

Attilio Giacosa, Antonella Riva, Giovanna Petrangolini, Pietro Allegrini, Teresa Fazia, Luisa Bernardinelli, Clara Gasparri, Milena Anna Faliva, Gabriella Peroni, Simone Perna and 1 more

Open access · goldAbstract read
In one paragraph

Article in Drugs in context, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Attilio GiacosaGastroenterology Unit, Policlinico di Monza, Monza, 20900 Italy.
Antonella RivaResearch and Development Unit, Indena SpA, Milan, 20139 Italy.
Giovanna PetrangoliniResearch and Development Unit, Indena SpA, Milan, 20139 Italy.
Pietro AllegriniResearch and Development Unit, Indena SpA, Milan, 20139 Italy.
Teresa FaziaDepartment of Brain and Behavioral Science, University of Pavia, Pavia, 27100 Italy.
Luisa BernardinelliDepartment of Brain and Behavioral Science, University of Pavia, Pavia, 27100 Italy.
Clara GasparriEndocrinology and Nutrition Unit, Azienda di Servizi alla Persona "Istituto Santa Margherita", University of Pavia, Pavia, 27100 Italy.
Milena Anna FalivaEndocrinology and Nutrition Unit, Azienda di Servizi alla Persona "Istituto Santa Margherita", University of Pavia, Pavia, 27100 Italy.
Gabriella PeroniEndocrinology and Nutrition Unit, Azienda di Servizi alla Persona "Istituto Santa Margherita", University of Pavia, Pavia, 27100 Italy.
Simone PernaDepartment of Biology, University of Bahrain, College of Science, Sakhir Campus P. O. Box, 32038 Kingdom of Bahrain.
Mariangela RondanelliIRCCS Mondino Foundation, Pavia, 27100 Italy.
Azienda di Servizi alla Persona di Pavia (Italy) · ITIndena (Italy) · ITUniversity of Pavia · ITFondazione Lanza · ITUniversity of Bahrain · BH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe treatment of symptomatic uncomplicated colonic diverticular disease (SUDD) is still under debate, and new data show a pathogenic role of dysbiosis and low-grade inflammation in intestinal mucosa. Recent research has highlighted the anti-inflammatory effects of botanical extracts such as

methodsIn a 30-day one-group longitudinal explanatory study, patients (men and women) were treated with an innovative association of CBP standardized extracts, 500 mg bid.

resultsTreatment of SUDD with the association of CBP was followed by a significant decrease in abdominal pain (p<0.0001). The study group showed that CBP supplementation was efficacious within 10 days and that efficacy was maintained almost constant until the 30th day of intervention.

conclusionA phytosome of curcumin and boswellia extracts may be useful for the relief of SUDD pain. However, controlled studies should be performed for final conclusions to be drawn.

Indexed as

Boswelliacurcumindietary supplementfood gradephytosomeSUDD

Identifiers

PMID33408751
PMCPMC7747791
OpenAlexW3113010726

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.