Evidence map›Paper›PMID 33408488›Full record

ArticleJournal of asthma and allergy2020

Got a Pen for Allergen Immunotherapy? Lessons from Near-Fatal Anaphylaxis with Pulmonary Edema.

Freerk Prenzel, Karl Nissler, Manuela Siekmeyer, Maike Vom Hove, Gudrun Schleicher, Wieland Kiess, Tobias Lipek

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of asthma and allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Freerk PrenzelDepartment of Pediatrics, University of Leipzig Medical Center, Leipzig, Germany.ORCID 0000-0002-2838-593X
Karl NisslerDepartment of Pediatrics, Sana Hospitals Leipzig Region, Borna, Germany.
Manuela SiekmeyerDepartment of Pediatrics, University of Leipzig Medical Center, Leipzig, Germany.
Maike Vom HoveDepartment of Pediatrics, University of Leipzig Medical Center, Leipzig, Germany.
Gudrun SchleicherPediatric Medical Practice, Rötha, Germany.
Wieland KiessDepartment of Pediatrics, University of Leipzig Medical Center, Leipzig, Germany.
Tobias LipekDepartment of Pediatrics, University of Leipzig Medical Center, Leipzig, Germany.
Leipzig University · DERoth and Rau (Germany) · DESana Kliniken Leipziger Land · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On our pediatric intensive care unit, we successfully treated a 10-year-old boy with severe pulmonary edema due to anaphylaxis after his last injection of a 3-year course of allergen immunotherapy (AIT). In view of the severity of the adverse event, we initiated a case analysis with all involved medical professionals. The evaluation revealed delayed administration of epinephrine due to dosing uncertainty and underestimation of severity. Consequently, all involved institutions established epinephrine auto-injectors (EAIs) in their emergency equipment. We suggest providing EAIs in every practice conducting AIT, as well as in pediatric emergency rooms and ambulances. We would like to remind readers of the risk of anaphylaxis, even on the last day of AIT.

Indexed as

allergen immunotherapyemergency equipmentepinephrine auto-injectorhouse dust mite

Identifiers

PMID33408488
PMCPMC7781355
OpenAlexW3115588942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.