Evidence map›Paper›PMID 33408482›Full record

ArticleOncoTargets and therapy2020

Circ_0001175 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis by Regulating miR-130a-5p.

Liheng Li, Ke He, Siliang Chen, Wenjiang Wei, Zuofu Tian, Yinghong Tang, Chengjiang Xiao, Guoan Xiang

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Liheng Li *Department of Interventional Radiology, Guangdong Second Provincial General Hospital, Guangzhou, People's Republic of China.
Ke He *Department of General Surgery, Guangdong Second Provincial General Hospital, Guangzhou, People's Republic of China.
Siliang ChenDepartment of Interventional Radiology, Guangdong Second Provincial General Hospital, Guangzhou, People's Republic of China.
Wenjiang WeiDepartment of Interventional Radiology, Guangdong Second Provincial General Hospital, Guangzhou, People's Republic of China.
Zuofu TianDepartment of Interventional Radiology, Guangdong Second Provincial General Hospital, Guangzhou, People's Republic of China.
Yinghong TangDepartment of Interventional Radiology, Guangdong Second Provincial General Hospital, Guangzhou, People's Republic of China.
Chengjiang XiaoDepartment of Interventional Radiology, Guangdong Second Provincial General Hospital, Guangzhou, People's Republic of China.
Guoan XiangDepartment of General Surgery, Guangdong Second Provincial General Hospital, Guangzhou, People's Republic of China.
Guangdong Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMany aberrantly expressed circular RNAs (circRNAs) play important roles in the development and progression of hepatocellular carcinoma (HCC). However, the exact function of circ_0001175 in HCC cells is unknown. Our study aimed to investigate the expression characteristics of circ_0001175 in HCC and its effects on the proliferation, migration and invasion of HCC cells, and to explore the potential mechanism. MATERIALS AND

methodsQuantitative real-time polymerase chain reaction (qRT-PCR) and Western blot were carried out to detect circ_0001175, microRNA-130a-5p (miR-130a-5p) and

resultsCirc_0001175 and

conclusionCirc_0001175 is highly expressed in HCC and facilitates HCC progression through regulating miR-130a-5p/

Indexed as

circ_0001175HCCmetastasismiR-130a-5pproliferation

Identifiers

PMID33408482
PMCPMC7781360
OpenAlexW3115402737

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.