Evidence map›Paper›PMID 33408408›Full record

ArticleNature2021

Design of biologically active binary protein 2D materials.

Ariel J Ben-Sasson, Joseph L Watson, William Sheffler, Matthew Camp Johnson, Alice Bittleston, Logeshwaran Somasundaram, Justin Decarreau, Fang Jiao, Jiajun Chen, Ioanna Mela and 10 more

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Proofreading and single-molecule sensitivity in T cell receptor signaling by condensate nucleation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Article
  15. Assembly and Functionality of 2D Protein Arrays.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Prediction of the Stability of Protein Substructures Using AI/ML Techniques.Methods in molecular biology (Clifton, N.J.) · 2025
    Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Ariel J Ben-SassonDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Joseph L WatsonMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID http://orcid.org/0000-0001-5492-0249
William ShefflerDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Matthew Camp JohnsonDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Alice BittlestonMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID http://orcid.org/0000-0002-1374-0222
Logeshwaran SomasundaramInstitute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA.
Justin DecarreauDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Fang JiaoPhysical Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.ORCID http://orcid.org/0000-0001-5087-6228
Jiajun ChenDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, USA.
Ioanna MelaDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-2914-9971
Andrew A DrabekDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
Sanchez M JarrettDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
Stephen C BlacklowDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6904-1981
Clemens F KaminskiDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-5194-0962
Greg L HuraMolecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
James J De YoreoDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-9541-733X
Justin M KollmanDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0350-5827
Hannele Ruohola-BakerDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-5588-4531
Emmanuel DeriveryMRC Laboratory of Molecular Biology, Cambridge, UK. derivery@mrc-lmb.cam.ac.uk.ORCID http://orcid.org/0000-0003-3927-5944
David BakerDepartment of Biochemistry, University of Washington, Seattle, WA, USA. dabaker@uw.edu.ORCID http://orcid.org/0000-0001-7896-6217

Funding

Progenitor Cell Biology Consortium Administrative Coordinating CenterU01HL099997 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI TERRIN, MICHAEL L · 2009 to 2015
$29.9M
User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6M
Self Renewal and Differentiation of Human Embryonic Stem CellsP01GM081619 · NIGMS · UNIVERSITY OF WASHINGTON · PI REH, THOMAS A · 2007 to 2017
$20.6M
Controlling Hematopoietic Lineage Commitment from ESC to PlateletsU01HL099993 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI TOROK-STORB, BEVERLY J. · 2009 to 2015
$8.3M
Notch Signaling in CancerR35CA220340 · NCI · HARVARD MEDICAL SCHOOL · PI BLACKLOW, STEPHEN C. · 2017 to 2023
$7.1M
The Structure and Function of Metabolic FilamentsR01GM118396 · NIGMS · UNIVERSITY OF WASHINGTON · PI KOLLMAN, JUSTIN M · 2016 to 2023
$2.9M
Acquisition of a high resolution, high throughput cryo-electron microscopeS10OD023476 · OD · UNIVERSITY OF WASHINGTON · PI KOLLMAN, JUSTIN M · 2017 to 2017
$2.0M
MicroRNA Function in Human Embryonic Stem CellsR01GM083867 · NIGMS · UNIVERSITY OF WASHINGTON · PI RUOHOLA-BAKER, HANNELE · 2008 to 2011
$1.5M
Acquisition of Embryonic Stem Cell Metabolic Signature - Minority SupplementR01GM097372 · NIGMS · UNIVERSITY OF WASHINGTON · PI RUOHOLA-BAKER, HANNELE · 2011 to 2014
$1.3M
Howard Hughes Medical InstituteMedical Research Council MC_UP_1201/13Medical Research Council MR/K015850/1Medical Research Council MR/K02292X/1NCI NIH HHS R35 CA220340NHLBI NIH HHS U01 HL099993NHLBI NIH HHS U01 HL099997NIGMS NIH HHS P01 GM081619NIGMS NIH HHS P30 GM124169NIGMS NIH HHS R01 GM083867NIGMS NIH HHS R01 GM097372NIGMS NIH HHS R01 GM118396NIH HHS S10 OD023476Wellcome Trust 203249/Z/16/Z
6 · The paper itself

Abstract

Ordered two-dimensional arrays such as S-layers

Indexed as

Drug DesignProtein Engineering3T3 CellsAnimalsCell BiologyCell SurvivalComputational BiologyEndocytosisEscherichia coliIn Vitro TechniquesKineticsLigandsMiceMicroscopy, Atomic ForceModels, MolecularProteinsLigandsProteins

Identifiers

PMID33408408
PMCPMC7855610

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.