ReviewNature reviews. Rheumatology2021
The impact of COVID-19 on rare and complex connective tissue diseases: the experience of ERN ReCONNET.
Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph
Review in Nature reviews. Rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 52 citations in OpenAlex.
- Crisis readiness for rare disease populations: learnings and recommendations by the European Reference Networks.The Lancet regional health. Europe · 2026Review
- The Role of Digital Tools and Their Implementation Within Patient Care Pathways for Rare Brain Disorders: The Case of Phenylketonuria.European journal of neurology · 2026Article
- Long Term Outcomes of Anti-COVID-19 Vaccines in Patients with Systemic Lupus Erythematosus: A Multicentre Study.Vaccines · 2025Article
- The organizational dimension in rare and complex diseases care management: an application of RarERN PathBMC health services research · 2025Article
- Multicentre retrospective detection of nailfold videocapillaroscopy abnormalities in long covid patients.RMD open · 2025Observational
- Factors Associated With Depression and Anxiety in People With Rare Diseases During COVID-19: A Cross-Sectional Study.Depression and anxiety · 2025Article
- Article
- The COVID-19 pandemic impact on continuity of care provision on rare brain diseases and on ataxias, dystonia and PKU. A scoping review.Orphanet journal of rare diseases · 2024Article
- A shock to the (health) system: experiences of adults with rare disorders during the first COVID-19 wave.Orphanet journal of rare diseases · 2024Article
- Systemic Lupus Erythematosus and Cytokine Storm.Advances in experimental medicine and biology · 2024Review
- Long-term outcomes of COVID-19 vaccination in patients with rare and complex connective tissue diseases: The ERN-ReCONNET VACCINATE study.Journal of translational autoimmunity · 2023Article
- A Clinical Qualification Protocol Highlights Overlapping Genomic Influences and Neuro-Autonomic Mechanisms in Ehlers-Danlos and Long COVID-19 Syndromes.Current issues in molecular biology · 2023Article
- Impact of COVID19 pandemic on patients with rare diseases in Spain, with a special focus on inherited metabolic diseases.Molecular genetics and metabolism reports · 2023Article
- The impact of COVID-19 on clinical course and treatment among patients with juvenile systemic sclerosis.Archives of rheumatology · 2023Article
- Evaluating chest pain in patients with post COVID conditions permission to think outside of the box.Journal of thrombosis and thrombolysis · 2023Article
- Involvement of the secosteroid vitamin D in autoimmune rheumatic diseases and COVID-19.Nature reviews. Rheumatology · 2023Review
- How Did the Two Years of the COVID-19 Pandemic Affect the Outcomes of the Patients with Inflammatory Rheumatic Diseases in Lithuania?Medicina (Kaunas, Lithuania) · 2023Article
- COVID-19's impact on care practice for alpha-1-antitrypsin deficiency patients.BMC health services research · 2023Article
- Editorial: Psychological impact and quality of life in rheumatic and musculoskeletal diseases.Frontiers in medicine · 2023Article
- Impact of the COVID-19 pandemic on the care of rare and undiagnosed diseases patients in France: a longitudinal population-based study.Orphanet journal of rare diseases · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
57 authors at 20 institutions in 8 countries.
Rosaria TalaricoRheumatology Unit, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
Silvia AguileraSpanish Association for Antiphospholipid Syndrome (SAF España), Elche, Spain.
Tobias AlexanderDepartment of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-1193-0097
Zahir AmouraDepartment of Internal Medicine, Hospital Pitié-Salpêtrière, Assistance Publique Hôpitaux de Paris, French National Referral Center for SLE and APS, Paris, France.
Ana M AntunesAuto-immune Disease Unit, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, EPE, Lisbon, Portugal.
Laurent ArnaudService de rhumatologie, Hôpitaux Universitaires de Strasbourg, Centre National de Référence des Maladies Systémiques et Auto-immunes Rares Grand-Est Sud-Ouest (RESO), Strasbourg, France.ORCID http://orcid.org/0000-0002-8077-8394
Tadej AvcinDepartment of Allergology, Rheumatology and Clinical Immunology, University Children's Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Lorenzo BerettaReferral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
Stefano BombardieriUniversity of Pisa, Pisa, Italy.
Gerd R BurmesterDepartment of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany.
Sara CannizzoRheumatology Unit, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
Lorenzo CavagnaDepartment of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Benjamin ChaigneService de Médecine Interne, Hôpital Cochin, Centre de Référence Maladies systémiques Autoimmunes Rares d'Ile de France, Assistance Publique-Hôpitaux de Paris (AP-HP), Université de Paris, Paris, France.
Alain CornetLupus Europe, Brussels, Belgium.
Nathalie Costedoat-ChalumeauService de Médecine Interne, Hôpital Cochin, Centre de Référence Maladies systémiques Autoimmunes Rares d'Ile de France, Assistance Publique-Hôpitaux de Paris (AP-HP), Université de Paris, Paris, France.
Andrea DoriaRheumatology Unit, Department of Medicine, University of Padova, Padova, Italy.
Alessandro FerrarisMedical Genetics Laboratory, Molecular Medicine Department, San Camillo Forlanini Hospital, Sapienza University, Rome, Italy.
Rebecca Fischer-BetzDepartment of Rheumatology, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
João E FonsecaRheumatology Department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon Academic Medical Centre, Lisbon, Portugal.
Charissa FrankFlemish Association for Hereditary Connective Tissue Disorders, Koersel, Belgium.
Andrea GagliotiRheumatology Unit, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
Ilaria GalettiFederation of European Scleroderma Associations (FESCA), Milan, Italy.
Jürgen GrunertDeutsche Ehlers-Danlos Initiative e.V., Furth, Germany.
Vera GuimarãesLiga Portuguesa Contra as Doenças Reumáticas, Lisbon, Portugal.
Eric HachullaDépartement de Médecine Interne et Immunologie Clinique, Centre de Référence des Maladies Systémiques et Auto-Immunes Rares du Nord-Ouest (CERAINO), LIRIC, INSERM, Univ. Lille, CHU Lille, Lille, France.
Frederic HoussiauDepartment of Rheumatology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Luca IaccarinoRheumatology Unit, Department of Medicine, University of Padova, Padova, Italy.
Thomas KriegDepartment of Dermatology, Universitätsklinikum, Cologne, Germany.
Marteen LimperDepartment of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Fransiska MalfaitCenter for Medical Genetics, Ghent University Hospital, Ghent, Belgium.ORCID http://orcid.org/0000-0002-5010-0304
Xavier MarietteUniversité Paris-Saclay, INSERM, CEA, Centre de recherche en Immunologie des infections virales et des maladies auto-immunes; AP-HP. Université Paris-Saclay, Hôpital Bicêtre, Rheumatology Department, Le Kremlin Bicêtre, Paris, France.
Diana MarinelloRheumatology Unit, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.ORCID http://orcid.org/0000-0002-5537-6043
Thierry MartinClinical immunology department, Hôpitaux Universitaires de Strasbourg, Centre National de Référence des Maladies Systémiques et Auto-immunes Rares Grand-Est Sud-Ouest (RESO), Strasbourg, France.
Lisa MatthewsRelapsing Polychondritis Awareness and Support, Worcester, UK.
Marco Matucci-CerinicDivision of Rheumatology and Scleroderma Unit, Department of Clinical and Experimental Medicine, AOU Careggi, University of Florence, Florence, Italy.
Alain MeyerService de rhumatologie, Hôpitaux Universitaires de Strasbourg, Centre National de Référence des Maladies Systémiques et Auto-immunes Rares Grand-Est Sud-Ouest (RESO), Strasbourg, France.
Carlomaurizio MontecuccoDepartment of Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Luc MouthonService de Médecine Interne, Hôpital Cochin, Centre de Référence Maladies systémiques Autoimmunes Rares d'Ile de France, Assistance Publique-Hôpitaux de Paris (AP-HP), Université de Paris, Paris, France.
Ulf Müller-LadnerDepartment of Rheumatology and Clinical Immunology, Kerckhoff Klinik, Justus Liebig University of Giessen, Bad Nauheim, Germany.
Simona RednicDepartment of Rheumatology, Emergency County Teaching Hospital, Cluj-Napoca, Romania.
Vasco C RomãoRheumatology Department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon Academic Medical Centre, Lisbon, Portugal.
Matthias SchneiderDepartment of Rheumatology, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Vanessa SmithDepartment of Rheumatology, Ghent University Hospital Department of Internal Medicine, Ghent, Belgium.
Alberto SulliResearch Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS Polyclinic Hospital San Martino, University of Genoa, Genoa, Italy.
Farah TamirouDepartment of Rheumatology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Domenica TaruscioNational Centre for Rare Diseases, Istituto Superiore di Sanità, Rome, Italy.
Anna V TaulaigoAuto-immune Disease Unit, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central, EPE, Lisbon, Portugal.
Enrique TerolDirectorate-General for Health and Food Safety, European Commission, Brussels, Belgium.
Angela TincaniRheumatology and Clinical Immunology Unit, ASST-Spedali Civili and University of Brescia, Brescia, Italy.
Simone TicciatiRheumatology Unit, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
Giuseppe TurchettiInstitute of Management, Scuola Superiore Sant'Anna, Pisa, Italy.
P Martin van HagenDepartment of Internal Medicine and Immunology, Erasmus MC, Rotterdam, Netherlands.
Jacob M van LaarDepartment of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Ana VieiraLiga Portuguesa Contra as Doenças Reumáticas, Núcleo Síndrome de Sjögren, Lisbon, Portugal.
Jeska K de Vries-BouwstraDepartment of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
Maurizio CutoloResearch Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS Polyclinic Hospital San Martino, University of Genoa, Genoa, Italy.
Marta MoscaRheumatology Unit, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy. ern.reconnet@ao-pisa.toscana.it.
Azienda Ospedaliera Universitaria Pisana · ITHôpitaux Universitaires de Strasbourg · FRUniversité Paris Cité · FRCentro Hospitalar Lisboa Norte · PTCharité - Universitätsmedizin Berlin · DECliniques Universitaires Saint-Luc · BEDüsseldorf University Hospital · DEGhent University Hospital · BEInserm · FROspedale Policlinico San Martino · ITPoliclinico San Matteo Fondazione · ITScuola Superiore Sant'Anna · ITUnidade Local de Saúde de São José · PTUniversity of Padua · ITUniversity of Pisa · ITUtrecht University · NLCarlo Forlanini Hospital · ITClinical Emergency Hospital Bucharest · ROErasmus MC · NLEuropean Commission · BE
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the COVID-19 pandemic, the need to provide high-level care for a large number of patients with COVID-19 has affected resourcing for, and limited the routine care of, all other conditions. The impact of this health emergency is particularly relevant in the rare connective tissue diseases (rCTDs) communities, as discussed in this Perspective article by the multi-stakeholder European Reference Network on Rare and Complex Connective Tissue and Musculoskeletal Diseases (ERN ReCONNET). The clinical, organizational and health economic challenges faced by health-care providers, institutions, patients and their families during the SARS-CoV-2 outbreak have demonstrated the importance of ensuring continuity of care in the management of rCTDs, including adequate diagnostics and monitoring protocols, and highlighted the need for a structured emergency strategy. The vulnerability of patients with rCTDs needs to be taken into account when planning future health policies, in preparation for not only the post-COVID era, but also any possible new health emergencies.
Indexed as
PandemicsSARS-CoV-2ComorbidityConnective Tissue DiseasesCOVID-19Delivery of Health CareHumans
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.