ArticleJournal of atherosclerosis and thrombosis2022
Tracking Pattern of Total Cholesterol Levels from Childhood to Adolescence in Japan.
Article in Journal of atherosclerosis and thrombosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Verification of the serum lipid tracking phenomenon by a follow-up survey using mail-in medical examinations for participants who underwent lifestyle-related disease prevention examinations as children.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026Article
- Association of Blood Arsenic Concentrations with Lipid Markers in Uruguayan Adolescents: Exploring Effect Modification by Body Mass Index and Sex.Exposure and health · 2026Article
- Tracking between cardiovascular-related measures at 4 and 8 years of age in the INMA-Asturias cohort.European journal of pediatrics · 2023Article
- Tracking of serum lipids in healthy children on a year-to-year basis.BMC cardiovascular disorders · 2023Article
- Relationships between Age at Menarche and Risk of Cardiovascular Disease Mortality among Japanese Women: The Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC) Study.Journal of atherosclerosis and thrombosis · 2023Article
- Case report: Unusual coexistence between familial hypercholesterolemia and familial hypobetalipoproteinemia.Frontiers in cardiovascular medicine · 2022Article
- Changes in Serum Cholesterol in Childhood and its Tracking to Adulthood.Journal of atherosclerosis and thrombosis · 2022Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThis study aimed to evaluate the tracking pattern of serum total cholesterol (TC) levels among Japanese children using data collected continuously for 9 years and examine the relationship between childhood and adulthood TC levels.
methodsTC levels of 2,608 first grade primary school children enrolled during 1981-2014 from two Japanese towns were measured during annual health check-ups. Nine-year trajectories of estimated TC levels stratified by TC quartiles in the first grade were analyzed using a mixed effects model. Adulthood TC levels were measured in participants who underwent health check-ups in the same area.
resultsOverall, 1,322 boys and 1,286 girls in the first grade of a primary school were followed for 9 years. Trajectories of TC levels during the period stratified by TC quartiles in the first grade differed significantly and did not cross each other for both sexes. Childhood data of 242 adult participants were linked with their adulthood data; the mean of age was late 20s for both sexes. The average TC levels in adulthood increased from the first to the fourth quartile in the first grade. Additionally, trajectories of TC levels differed between boys and girls. The later the admission year, the more elevated the TC levels in girls.
conclusionAmong Japanese children, TC levels were strongly tracked from childhood to adolescence for 9 years, and elevated TC levels in childhood were related to elevated TC levels in adulthood. Maintaining appropriate TC levels during childhood may be important to prevent future coronary artery diseases.
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