ArticleBMJ open2021
Prognostic factors for recovery of health status after injury: a prospective multicentre cohort study.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02508675 (Prevalence, Recovery Patterns and Risk Factors of Non-fatal Outcome and Costs After Trauma; a Prospective Follow up Study), which is not on this map. Cited by 10 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence, Recovery Patterns and Risk Factors of Non-fatal Outcome and Costs After Trauma; a Prospective Follow up Study
Who cites it
10 citing papers in PubMed.
- Physical functionality two years after major trauma: predictors from a single center cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Mechanisms of inflammatory response in secondary brain injury: a review of computational approaches, challenges, and future directions.Biomechanics and modeling in mechanobiology · 2026Review
- Health-related quality of life in patients undergoing surgery for upper extremity bone tumors: A cross-sectional study.Joint diseases and related surgery · 2026Article
- Healthcare and productivity costs among Canadian road trauma survivors over the year following injury.Scientific reports · 2025Article
- Determinants of Economic Costs Following Road Traffic Injuries in Canada: A Quantile Regression Forests Machine Learning Approach.ClinicoEconomics and outcomes research : CEOR · 2025Article
- The effect of recombinant erythropoietin on long-term outcome after moderate-to-severe traumatic brain injury.Intensive care medicine · 2023Article
- Exploring factors influencing health-related quality of life in adult females with injuries: a cross-sectional nationwide study.Frontiers in public health · 2023Article
- Assessing independence in mobility activities in trauma care: Validity and reliability of the Activity Independence Measure-Trauma (AIM-T) in humanitarian settings.PLOS global public health · 2023Article
- Innovative Technologies in the Neurorehabilitation of Traumatic Brain Injury: A Systematic Review.Brain sciences · 2022Review
- Clustering of trauma patients based on longitudinal data and the application of machine learning to predict recovery.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine prognostic factors for health status and recovery patterns during the first 2 years after injury in the clinical trauma population.
designA prospective longitudinal cohort study.
settingTen participating hospitals in Brabant, the Netherlands.
participantsInjured adult patients admitted to a hospital between August 2015 and November 2016 were followed: 4883 (50%) patients participated.
main outcome measuresPrimary outcome was health status, measured with the EuroQol-5-dimensions-3-levels (EQ-5D), including a cognition item and the EuroQol Visual Analogue Scale. Health status was collected at 1 week, 1, 3, 6, 12 and 24 months after injury. Potential prognostic factors were based on literature and clinical experience (eg, age, sex, pre-injury frailty (Groningen Frailty Index), pre-injury EQ-5D).
resultsHealth status increased mainly during the first 6 months after injury with a mean EQ-5D utility score at 1 week of 0.49 and 0.79 at 24 months. The dimensions mobility, pain/discomfort and usual activities improved up to 2 years after injury. Lower pre-injury health status, frailty and longer length of stay at the hospital were important prognostic factors for poor recovery. Spine injury, lower and upper extremity injury showed to be prognostic factors for problems after injury. Traumatic brain injury was a prognostic factor for cognitive problems.
conclusionThis study contributes to the increase in knowledge of health recovery after injury. It could be a starting point to develop prediction models for specific injury classifications and implementation of personalised medicine. TRIAL REGISTRATION NUMBER: NCT02508675.
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