Evidence map›Paper›PMID 33407966›Full record

ArticleParasitology2021

Differences in mitochondrial NADH dehydrogenase activities in trypanosomatids.

Petra Čermáková, Anna Maďarová, Peter Baráth, Jana Bellová, Vyacheslav Yurchenko, Anton Horváth

Open access · hybridAbstract read
In one paragraph

Article in Parasitology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

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  10. Frontiers in molecular biosciences · 2023
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  13. Proceedings of the National Academy of Sciences of the United States of America · 2021
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  16. The Remarkable Metabolism ofPathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Petra ČermákováDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.
Anna MaďarováDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.
Peter BaráthInstitute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia.
Jana BellováInstitute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia.
Vyacheslav YurchenkoFaculty of Science, Life Science Research Centre, University of Ostrava, Ostrava, Czech Republic.ORCID 0000-0003-4765-3263
Anton HorváthDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.ORCID 0000-0003-0785-4204
Comenius University Bratislava · SKInstitute of Chemistry of the Slovak Academy of Sciences · SKSechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complex I (NADH dehydrogenase) is the first enzyme in the respiratory chain. It catalyses the electron transfer from NADH to ubiquinone that is associated with proton pumping out of the matrix. In this study, we characterized NADH dehydrogenase activity in seven monoxenous trypanosomatid species: Blechomonas ayalai, Herpetomonas tarakana, Kentomonas sorsogonicus, Leptomonas seymouri, Novymonas esmeraldas, Sergeia podlipaevi and Wallacemonas raviniae. We also investigated the subunit composition of the complex I in dixenous Phytomonas serpens, in which its presence and activity have been previously documented. In addition to P. serpens, the complex I is functionally active in N. esmeraldas and S. podlipaevi. We also identified 24-32 subunits of the complex I in individual species by using mass spectrometry. Among them, for the first time, we recognized several proteins of the mitochondrial DNA origin.

Indexed as

Mitochondrial ProteinsNADH DehydrogenaseProtozoan ProteinsSpecies SpecificityTrypanosomatinaMitochondrial ProteinsNADH DehydrogenaseProtozoan ProteinsMonoxenous trypanosomatidsNADH dehydrogenasePhytomonas

Identifiers

PMID33407966
PMCPMC8312217
OpenAlexW3118469323

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.