Evidence map›Paper›PMID 33407923›Full record

ArticlePilot and feasibility studies2021

CardiO Cycle: a pilot feasibility study of in-bed cycling in critically ill patients post cardiac surgery.

Anastasia N L Newman, Michelle E Kho, Jocelyn E Harris, Nasim Zamir, Ellen McDonald, Alison Fox-Robichaud, Patricia Solomon, Canadian Critical Care Trials Group

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pilot and feasibility studies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02976415 (CardiO Cycle), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02976415 nacompletednot on this map

CardiO Cycle: A Pilot Safety and Feasibility Study of In-Bed Cycling in Patients Post Cardiac Surgery

TypeinterventionalSponsorHamilton Health Sciences CorporationRan2017 to 2019Enrolled23ConditionsCardiac Disease, Critical Illness, Critical Illness Polyneuropathy, Critical Illness MyopathyArmsIn-Bed Cycling
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Core sociodemographic data variables reported in Canadian intensive care unit studies: a scoping review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Anastasia N L NewmanSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada. newmanan@mcmaster.ca.ORCID http://orcid.org/0000-0003-0810-8131
Michelle E KhoSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
Jocelyn E HarrisSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
Nasim ZamirCollege of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Ellen McDonaldDepartment of Medicine, Division of Critical Care, McMaster University, Hamilton, Ontario, Canada.
Alison Fox-RobichaudHamilton General Hospital, Hamilton, Ontario, Canada.
Patricia SolomonSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
Canadian Critical Care Trials Group
Hamilton General Hospital · CAMcMaster University · CAUniversity of Saskatchewan · CASt. Joseph’s Healthcare Hamilton · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn-bed cycling is a novel modality for the initiation of early mobilization in the intensive care unit. No study has investigated its use in the critically ill, off-track post cardiac surgery population. Before conducting an effectiveness trial, feasibility data are needed. The aim of this study was to determine the feasibility of in-bed cycling in a population of off-track cardiac surgery patients.

methodsWe conducted a prospective feasibility study in a 16-bed adult cardiac surgery intensive care unit in Ontario, Canada. Previously ambulatory adults (≥ 18 years) who were mechanically ventilated for ≥ 72 h were enrolled within 3 to 7 days post cardiac surgery. Twenty minutes of in-bed cycling was delivered by ICU physiotherapists 5 days/week. The primary outcome, feasibility, was the percent of patient-cycling sessions that occurred when cycling was appropriate. The secondary outcome was cycling safety, measured as cycling discontinuation due to predetermined adverse events.

resultsWe screened 2074 patients, 29 met eligibility criteria, and 23 (92%) consented. Patients were male (78.26%) with a median [IQR] age of 76 [11] years, underwent isolated coronary bypass (39.1%), and had a median EuroScore II of 5.4 [7.8]. The mean (SD) time post-surgery to start of cycling was 5.9 (1.4) days. Patients were cycled on 80.5% (136/169) of eligible days, with limited physiotherapy staffing accounting for 48.5% of the missed patient-cycling sessions. During 136 sessions of cycling, 3 adverse events occurred in 3 individual patients. The incidence of an adverse event was 2.2 per 100 patient-cycling sessions (95% CI 0.50, 6.4).

conclusionsIn-bed cycling with critically ill cardiac surgery patients is feasible with adequate physiotherapy staffing and appears to be safe. Future studies are needed to determine the effectiveness of this intervention in a larger sample.

trial registrationThis trial was registered with Clinicaltrials.gov ( NCT02976415 ). Registered November 29, 2016.

Indexed as

Cardiac surgeryCritical careIntensive care unitPhysiotherapyRehabilitation

Identifiers

PMID33407923
PMCPMC7788703
OpenAlexW3119375854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.