Evidence map›Paper›PMID 33407910›Full record

ArticleJournal of eating disorders2021

An open trial of app-assisted acceptance and commitment therapy (iACT) for eating disorders in type 1 diabetes.

Rhonda M Merwin, Ashley A Moskovich, Michael Babyak, Mark Feinglos, Lisa K Honeycutt, Jan Mooney, Sara P Freeman, Heather Batchelder, Devdutta Sangvai

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of eating disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02980627 (iOmit), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02980627 nacompletednot on this map

iOmit: Reducing Intentional Insulin Misuse in Type 1 Diabetes

TypeinterventionalSponsorDuke UniversityRan2016 to 2019Enrolled27ConditionsType 1 Diabetes Mellitus, Eating DisordersArmsTherapy with Mobile App Enhancement
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rhonda M MerwinDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, DUMC Box 3842, Durham, NC, 27712, USA. rhonda.merwin@duke.edu.ORCID http://orcid.org/0000-0002-3729-0297
Ashley A MoskovichDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, DUMC Box 3842, Durham, NC, 27712, USA.
Michael BabyakDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, DUMC Box 3842, Durham, NC, 27712, USA.
Mark FeinglosDepartment of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University Medical Center, Durham, NC, USA.
Lisa K HoneycuttDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, DUMC Box 3842, Durham, NC, 27712, USA.
Jan MooneyDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, DUMC Box 3842, Durham, NC, 27712, USA.
Sara P FreemanDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, DUMC Box 3842, Durham, NC, 27712, USA.
Heather BatchelderDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, DUMC Box 3842, Durham, NC, 27712, USA.
Devdutta SangvaiDepartment of Family Medicine and Community Health, Duke University Medical Center, Durham, NC, USA.
Duke Medical Center · USDuke University · US

Funding

iOmit: Reducing Intentional Insulin Misuse in Type 1 DiabetesR21DK106603 · NIDDK · DUKE UNIVERSITY · PI MERWIN, RHONDA M · 2016 to 2017
$437k
NIDDK NIH HHS R21 DK106603NIDDK NIH HHS R21DK106603
6 · The paper itself

Abstract

backgroundEating disorders (EDs) among individuals with type 1 diabetes (T1D) increase the risk of early and severe diabetes-related medical complications and premature death. Conventional eating disorder (ED) treatments have been largely ineffective for T1D patients, indicating the need to tailor treatments to this patient population and the unique conditions under which ED symptoms emerge (in the context of a chronic illness with unrelenting demands to control blood glucose, diet and exercise). The current study was a pilot open trial of iACT, a novel intervention for EDs in T1D grounded in Acceptance and Commitment Therapy (ACT). iACT was based on the premise that ED symptoms emerge as individuals attempt to cope with T1D and related emotional distress. iACT taught acceptance and mindfulness as an alternative to maladaptive avoidance and control, and leveraged personal values to increase willingness to engage in T1D management, even when it was upsetting (e.g., after overeating). A tailored mobile application ("app") was used in between sessions to facilitate the application of ACT skills in the moment that individuals are making decisions about their diabetes management.

methodsAdults with T1D who met criteria for an ED completed 12 sessions of iACT (with three optional tapering sessions). In addition to examining whether treatment was acceptable and feasible (the primary aim of the study), the study also examined whether iACT was associated with increased psychological flexibility (i.e., the ability to have distressing thoughts/feelings about diabetes while pursuing personally meaningful values), and improvements in ED symptoms, diabetes management and diabetes distress.

resultsTreatment was acceptable to T1D patients with EDs and feasible to implement. Participants reported increased psychological flexibility with diabetes-related thoughts/feelings, and less obstruction and greater progress in pursuing personal values. There were large effects for change in ED symptoms, diabetes self-management and diabetes distress from baseline to end-of-treatment (Cohen's d = .90-1.79). Hemoglobin A

conclusionsFindings provide preliminary evidence for iACT to improve outcomes for T1D patients with EDs and support further evaluation of this approach in a controlled trial.

trial registrationNCT02980627 . Registered 8 July 2016.

Indexed as

Acceptance and commitment therapyDiabetes distressEating disordersExperiential avoidanceMobile healthPsychological flexibilityType 1 diabetes

Identifiers

PMID33407910
PMCPMC7789378
OpenAlexW3120361910

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.