Evidence map›Paper›PMID 33407849›Full record

ArticleBMC research notes2021

Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru.

Hugo Carrillo-Ng, Lorena Becerra-Goicochea, Yordi Tarazona-Castro, Luis Pinillos-Vilca, Luis J Del Valle, Miguel Angel Aguilar-Luis, Carmen Tinco-Valdez, Wilmer Silva-Caso, Johanna Martins-Luna, Isaac Peña-Tuesta and 2 more

Abstract read
In one paragraph

Article in BMC research notes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hugo Carrillo-NgSchool of Medicine, Research and Innovation Center of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos Cuadra 2, Chorrillos, Lima, Peru.
Lorena Becerra-GoicocheaHospital Regional Docente de Cajamarca, Cajamarca, Peru.
Yordi Tarazona-CastroLaboratorio de Biologia Molecular, Instituto de Investigación Nutricional, Lima, Peru.
Luis Pinillos-VilcaHospital Regional Docente de Cajamarca, Cajamarca, Peru.
Luis J Del ValleDepartament d'Enginyeria Química, EEBE, Barcelona Research Center for Multiscale Science and Engineering, Universitat Politècnica de Catalunya (UPC), Barcelona, Spain.
Miguel Angel Aguilar-LuisSchool of Medicine, Research and Innovation Center of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos Cuadra 2, Chorrillos, Lima, Peru.
Carmen Tinco-ValdezSchool of Medicine, Research and Innovation Center of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos Cuadra 2, Chorrillos, Lima, Peru.
Wilmer Silva-CasoSchool of Medicine, Research and Innovation Center of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos Cuadra 2, Chorrillos, Lima, Peru. gian_will@hotmail.com.
Johanna Martins-LunaSchool of Medicine, Research and Innovation Center of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos Cuadra 2, Chorrillos, Lima, Peru.
Isaac Peña-TuestaSchool of Medicine, Research and Innovation Center of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos Cuadra 2, Chorrillos, Lima, Peru.
Ronald Aquino-OrtegaSchool of Medicine, Research and Innovation Center of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos Cuadra 2, Chorrillos, Lima, Peru.
Juana Del Valle-MendozaSchool of Medicine, Research and Innovation Center of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos Cuadra 2, Chorrillos, Lima, Peru. juana.delvalle@upc.pe.ORCID http://orcid.org/0000-0002-6011-5040

Funding

Incentives for Research of the Universidad Peruana de Ciencias Aplicadas A-069-2020-UPC
6 · The paper itself

Abstract

objectiveTo characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus.

resultsA total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).

Indexed as

MicrobiotaPapillomavirus InfectionsUterine Cervical NeoplasmsCervix UteriFemaleHumansPapillomaviridaePeruCervical cancerHPVHuman papillomavirusMicrobiotaPCRPeru

Identifiers

PMID33407849
PMCPMC7788800

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.