ReviewSkeletal muscle2021
Muscle spindle function in healthy and diseased muscle.
Review in Skeletal muscle, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed.
- Effect of cervical traction on balance parameters in patients with cervical radiculopathy: a randomized controlled trial.BMC musculoskeletal disorders · 2025Trial
- Vibration-induced illusion of movement is hindered by acute stroke but mostly by aging: a cross-sectional study.Aging clinical and experimental research · 2025Trial
- Modified tibiofibular synostosis vs. Burgess stump in a bilateral amputee: a case report.BMC musculoskeletal disorders · 2026Article
- Tibialis Cranialis Extrafusal and Intrafusal Myofibers and Muscle Spindle Pathology in Canine Degenerative Myelopathy.Animals : an open access journal from MDPI · 2026Article
- Cellular and molecular mechanisms of muscle spindle development and function.Physiology (Bethesda, Md.) · 2026Review
- Muscle Spindle Alterations Following Ischemic Stroke and Peripheral Denervation in Murine Models.International journal of molecular sciences · 2026Article
- Impaired trunk sensorimotor control during isometric force reproduction involving rotation and extension in adolescents with idiopathic scoliosis.North American Spine Society journal · 2026Article
- Cortical neuromodulation by vibration-induced illusion of movement is observed in older individuals, but not in individuals with acute stroke: a cross-sectional fNIRS study.Journal of neuroengineering and rehabilitation · 2026Article
- Histomorphological Effects of Repeated Administration of the TRPA1 Antagonist HC-030031 on Intrafusal and Extrafusal Muscle Fibers in Healthy Young Rats.Muscles (Basel, Switzerland) · 2026Article
- Muscle Tone Regulation and Bruxism in Chronic Stress: Pathophysiological Links to Tooth Fractures and Dental Hard Tissue Pathology.Medical sciences (Basel, Switzerland) · 2026Review
- Whole-Mount Optical Clearing of Rabbit Tenuissimus Muscle for Assessment of Muscle Spindle Morphology.bioRxiv : the preprint server for biology · 2026Article
- Neural and Mechanical Adaptations During Static Stretching With Different Amplitudes.The European journal of neuroscience · 2026Article
- Medial Pterygoid Muscles Penetration by Tubero-Pterygoid Implants: Clinical, Anatomical and Statistical Insights Regarding Temporo-Mandibular Disorders (TMDs).Life (Basel, Switzerland) · 2026Article
- Age-related changes in hand function - it's not just about muscle strength.Frontiers in human neuroscience · 2026Review
- Aberrant skeletal muscle morphogenesis and myofiber differentiation characterize equine myotonic dystrophy.PloS one · 2026Article
- Whole-mount optical clearing of rabbit tenuissimus muscle for assessment of muscle spindle morphology.Frontiers in neuroscience · 2026Article
- Exploring neuronal mechanisms of osteosarcopenia in older adults.The Journal of physiology · 2026Review
- Bio-Inspired Artificial Muscle-Tendon Complex of Liquid Crystal Elastomer for Bidirectional Afferent-Efferent Signaling.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Review
- Impact of Hyaluronic Acid Lip Filling on the Electromyographic Activity of the Orbicularis Oris Muscle in Adult Women.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Almost every muscle contains muscle spindles. These delicate sensory receptors inform the central nervous system (CNS) about changes in the length of individual muscles and the speed of stretching. With this information, the CNS computes the position and movement of our extremities in space, which is a requirement for motor control, for maintaining posture and for a stable gait. Many neuromuscular diseases affect muscle spindle function contributing, among others, to an unstable gait, frequent falls and ataxic behavior in the affected patients. Nevertheless, muscle spindles are usually ignored during examination and analysis of muscle function and when designing therapeutic strategies for neuromuscular diseases. This review summarizes the development and function of muscle spindles and the changes observed under pathological conditions, in particular in the various forms of muscular dystrophies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.