ArticleBiotechnology for biofuels2021
Biomass, lipid accumulation kinetics, and the transcriptome of heterotrophic oleaginous microalga Tetradesmus bernardii under different carbon and nitrogen sources.
Article in Biotechnology for biofuels, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 47 citations in OpenAlex.
- Combined transcriptomic and proteomic analysis reveals the influence of sulfur availability on nitrogen and carbon metabolism and lipid accumulation in Tribonema minus (Xanthophyceae).Biotechnology for biofuels and bioproducts · 2026Article
- Process Engineering Strategies for Microbial Lipid Production: From Strain Evolution to Industrial-Scale Bioprocessing.International journal of molecular sciences · 2026Review
- Decoding nitrogen depletion-induced lipid accumulation in Aurantiochytrium sp. YHPM1 through integrated proteomic and transcriptomic analyses.BMC microbiology · 2026Article
- Influence of Nutrient Medium Composition on the Redistribution of Valuable Metabolites in the Freshwater Green AlgaBiotech (Basel (Switzerland)) · 2025Article
- Laminaria Japonica hydrolysate as a novel biostimulant for enhancing DHA accumulation in Aurantiochytrium limacinum.World journal of microbiology & biotechnology · 2025Article
- Nanomedicines Targeting Metabolic Pathways in the Tumor Microenvironment: Future Perspectives and the Role of AI.Metabolites · 2025Review
- Potential of Lipid Biosynthesis under Heterotrophy in the Marine DiatomACS sustainable chemistry & engineering · 2023Article
- Optimization of Heterotrophic Culture Conditions for the MicroalgaeMarine drugs · 2023Article
- Growth Behavior, Biomass Composition and Fatty Acid Methyl Esters (FAMEs) Production Potential ofMarine drugs · 2023Article
- The growth, lipid accumulation and adaptation mechanism in response to variation of temperature and nitrogen supply in psychrotrophic filamentous microalga Xanthonema hormidioides (Xanthophyceae).Biotechnology for biofuels and bioproducts · 2023Article
- Coculturing of Mucor plumbeus and Bacillus subtilis bacterium as an efficient fermentation strategy to enhance fungal lipid and gamma-linolenic acid (GLA) production.Scientific reports · 2022Article
- Metabolic and Proteomic Analysis ofMolecules (Basel, Switzerland) · 2022Article
- Evaluation of Different Standard Amino Acids to Enhance the Biomass, Lipid, Fatty Acid, and γ-Linolenic Acid Production inFrontiers in nutrition · 2022Article
- Developing algae as a sustainable food source.Frontiers in nutrition · 2022Review
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6 authors at 2 institutions in 1 country.
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Abstract
backgroundHeterotrophic cultivation of microalgae has been proposed as a viable alternative method for novel high-value biomolecules, enriched biomass, and biofuel production because of their allowance of high cell density levels, as well as simple production technology. Tetradesmus bernardii, a newly isolated high-yielding oleaginous microalga under photoautotrophic conditions, is able to grow heterotrophically, meaning that it can consume organic carbon sources in dark condition. We investigated the effect of different carbon/nitrogen (C/N) ratios on the growth and lipid accumulation of T. bernardii in heterotrophic batch culture under two nitrogen sources (NaNO
resultsT. bernardii can accumulate high biomass concentrations in heterotrophic batch culture where the highest biomass of 46.09 g/L was achieved at 100 g/L glucose concentration. The rate of glucose to biomass exceeded 55% when the glucose concentration was less than 80 g/L, and the C/N ratio was 44 at urea treatment. The culture was beneficial to lipid accumulation at a C/N ratio between 110 and 130. NaNO
conclusionT. bernardii exhibited rapid growth and high lipid accumulation in heterotrophic culture. It may be a potential candidate for biomass and biofuel production. Transcriptome analysis showed that multilevel regulation ensured the conversion from carbon to the synthesis of carbohydrate and lipid.
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