Evidence map›Paper›PMID 33407759›Full record

ReviewScandinavian journal of trauma, resuscitation and emergency medicine2021

Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): update and insights into current practices and future directions for research and implementation.

Marianne A Thrailkill, Kevin H Gladin, Catherine R Thorpe, Teryn R Roberts, Jae H Choi, Kevin K Chung, Corina N Necsoiu, Todd E Rasmussen, Leopoldo C Cancio, Andriy I Batchinsky

Open access · goldAbstract readReview
In one paragraph

Review in Scandinavian journal of trauma, resuscitation and emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 45 citations in OpenAlex.

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  9. Selective aortic arch perfusion: a first-in-human observational cadaveric study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Marianne A ThrailkillGlacier Technical Solutions, El Paso, TX, USA.
Kevin H GladinUnited States Air Force, Bethesda, MD, USA.
Catherine R ThorpeExtracorporeal Life Support Capability Area, United States Army Institute of Surgical Research, JBSA Ft. Sam Houston, San Antonio, TX, 78234, USA.
Teryn R RobertsExtracorporeal Life Support Capability Area, United States Army Institute of Surgical Research, JBSA Ft. Sam Houston, San Antonio, TX, 78234, USA.
Jae H ChoiExtracorporeal Life Support Capability Area, United States Army Institute of Surgical Research, JBSA Ft. Sam Houston, San Antonio, TX, 78234, USA.
Kevin K ChungUniformed Services University of the Health Sciences, Bethesda, MD, USA.
Corina N NecsoiuProlonged Field Care Capability Area, United States Army Institute of Surgical Research, JBSA Ft. Sam Houston, San Antonio, TX, USA.
Todd E RasmussenUniformed Services University of the Health Sciences, Bethesda, MD, USA.
Leopoldo C CancioUnited States Army Institute of Surgical Research, JBSA Ft. Sam Houston, San Antonio, TX, USA.
Andriy I BatchinskyExtracorporeal Life Support Capability Area, United States Army Institute of Surgical Research, JBSA Ft. Sam Houston, San Antonio, TX, 78234, USA. andriy.i.batchinsky.civ@mail.mil.
United States Army Institute of Surgical Research · USImation (United States) · USUniformed Services University of the Health Sciences · USOak Ridge Associated Universities · USThe Geneva Foundation · USUnited States Air Force · US

Funding

Air Force Office of Scientific Research FA9550-20-0065
6 · The paper itself

Abstract

backgroundIn this review, we assess the state of Resuscitative Endovascular Occlusion of the Aorta (REBOA) today with respect to out-of-hospital (OOH) vs. inhospital (H) use in blunt and penetrating trauma, as well as discuss areas of promising research that may be key in further advancement of REBOA applications.

methodsTo analyze the trends in REBOA use, we conducted a review of the literature and identified articles with human or animal data that fit the respective inclusion and exclusion criteria. In separate tables, we compiled data extracted from selected articles in categories including injury type, zone and duration of REBOA, setting in which REBOA was performed, sample size, age, sex and outcome. Based on these tables as well as more detailed review of some key cases of REBOA usage, we assessed the current state of REBOA as well as coagulation and histological disturbances associated with its usage. All statistical tests were 2-sided using an alpha=0.05 for significance. Analysis was done using SAS 9.5 (Cary, NC). Tests for significance was done with a t-test for continuous data and a Chi Square Test for categorical data.

resultsIn a total of 44 cases performed outside of a hospital in both military and civilian settings, the overall survival was found to be 88.6%, significantly higher than the 50.4% survival calculated from 1,807 cases of REBOA performed within a hospital (p<.0001). We observe from human data a propensity to use Zone I in penetrating trauma and Zone III in blunt injuries. We observe lower final metabolic markers in animal studies with shorter REBOA time and longer follow-up times.

conclusionsFurther research related to human use of REBOA must be focused on earlier initiation of REBOA after injury which may depend on development of rapid vascular access devices and techniques more so than on any new improvements in REBOA. Future animal studies should provide detailed multisystem organ assessment to accurately define organ injury and metabolic burden associated with REBOA application. Overall, animal studies must involve realistic models of injury with severe clinical scenarios approximating human trauma and exsanguination, especially with long-term follow-up after injury.

Indexed as

AortaBalloon OcclusionEmergency Medical ServicesEndovascular ProceduresFemaleHumansMaleWounds, NonpenetratingWounds, PenetratingNon-compressible torso hemorrhageREBOA

Identifiers

PMID33407759
PMCPMC7789715
OpenAlexW3118701459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.