ArticleScandinavian journal of trauma, resuscitation and emergency medicine2021
Validation of the BATT score for prehospital risk stratification of traumatic haemorrhagic death: usefulness for tranexamic acid treatment criteria.
Article in Scandinavian journal of trauma, resuscitation and emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05820217 (External Validation of the Clinical Pre-hospital "Red- Flag" Alert for Activation of Intra-hospital Hemorrhage Control Response in Blunt Trauma. A Prospective Multicentric Study), which is not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
External Validation of the Clinical Pre-hospital "Red- Flag" Alert for Activation of Intra-hospital Hemorrhage Control Response in Blunt Trauma. A Prospective Multicentric Study
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Tranexamic acid in trauma: A joint position statement and resource document of NAEMSP, ACEP, and ACS-COT.The journal of trauma and acute care surgery · 2025Guideline
- Factors that influence the administration of tranexamic acid (TXA) to trauma patients in prehospital settings: a systematic review.BMJ open · 2023Pooled it
- Effects of tranexamic acid treatment in severely and non-severely injured trauma patients.Transfusion · 2022Pooled it
- Adherence to strong recommendations of the German Polytrauma Guideline: an analysis of TraumaRegister DGU data over a decade.Scientific reports · 2026Article
- Machine learning for prehospital prediction of trauma-induced coagulopathy: a national evaluation of the potential impact on tranexamic acid administration.Trauma surgery & acute care open · 2026Article
- On-scene machine learning prediction model for massive transfusion in trauma and its association with in-hospital mortality.BJS open · 2025Article
- Prehospital transfusion: an 8-year descriptive retrospective monocenter study.BMC emergency medicine · 2025Article
- Validation of the FASILA Score for Predicting Interventions and Outcomes in Traumatic Abdominal and Pelvic Injuries: A Prospective Clinical Study.World journal of surgery · 2025Article
- Article
- Prehospital undertriage of older injured patients in western Switzerland: an observational cross-sectional study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Observational
- Evaluation of the prehospital administration of tranexamic acid for injured patients: a state-wide observational study with sex and age-disaggregated analysis.Emergency medicine journal : EMJ · 2024Observational
- Urgent action needed on prehospital tranexamic acid in trauma.Emergency medicine journal : EMJ · 2024Article
- The predictive value of four traumatic hemorrhage scores for early massive blood transfusion in trauma patients in the pre-hospital setting.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- The use of whole body computed tomography does not lead to increased 24-h mortality in severely injured patients in circulatory shock.Scientific reports · 2024Observational
- Early identification of bleeding in trauma patients: external validation of traumatic bleeding scores in the Swiss Trauma Registry.Critical care (London, England) · 2022Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundTranexamic acid reduces surgical blood loss and reduces deaths from bleeding in trauma patients. Tranexamic acid must be given urgently, preferably by paramedics at the scene of the injury or in the ambulance. We developed a simple score (Bleeding Audit Triage Trauma score) to predict death from bleeding.
methodsWe conducted an external validation of the BATT score using data from the UK Trauma Audit Research Network (TARN) from 1st January 2017 to 31st December 2018. We evaluated the impact of tranexamic acid treatment thresholds in trauma patients.
resultsWe included 104,862 trauma patients with an injury severity score of 9 or above. Tranexamic acid was administered to 9915 (9%) patients. Of these 5185 (52%) received prehospital tranexamic acid. The BATT score had good accuracy (Brier score = 6%) and good discrimination (C-statistic 0.90; 95% CI 0.89-0.91). Calibration in the large showed no substantial difference between predicted and observed death due to bleeding (1.15% versus 1.16%, P = 0.81). Pre-hospital tranexamic acid treatment of trauma patients with a BATT score of 2 or more would avoid 210 bleeding deaths by treating 61,598 patients instead of avoiding 55 deaths by treating 9915 as currently.
conclusionThe BATT score identifies trauma patient at risk of significant haemorrhage. A score of 2 or more would be an appropriate threshold for pre-hospital tranexamic acid treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.