Evidence map›Paper›PMID 33407704›Full record

SynthesisJournal of orthopaedic surgery and research2021

Factors affecting the incidence of postoperative periprosthetic fractures following primary and revision hip arthroplasty: a systematic review and meta-analysis.

Christos Bissias, Angelos Kaspiris, Athanasios Kalogeropoulos, Konstantinos Papoutsis, Nikolaos Natsioulas, Konstantinos Barbagiannis, Panayiotis J Papagelopoulos, Olga D Savvidou

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Alkaline Phosphatase is an Independent Risk Factor for Periprosthetic Fractures in Total Joint Arthroplasty.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2023
    Article
  13. Review
  14. Atypical Vancouver B1 Periprosthetic Fractures: The Unsolved Problem.Geriatric orthopaedic surgery & rehabilitation · 2023
    Article
  15. Narrative Review of the Mechanism of Hip Prosthesis Dislocation and Methods to Reduce the Risk of Dislocation.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Christos BissiasDepartment of Orthopaedic Surgery, Naval Hospital of Athens, Deinokratous 70, 115 21, Athens, Greece. chrisbis@hotmail.com.
Angelos KaspirisLaboratory of Molecular Pharmacology/Division for Orthopaedic Research, School of Health Sciences, University of Patras, 26504, Patras, Greece.ORCID http://orcid.org/0000-0003-3265-5522
Athanasios KalogeropoulosSonnenhof Spital, Bern, Switzerland.
Konstantinos PapoutsisDepartment of Orthopaedic Surgery, Naval Hospital of Athens, Deinokratous 70, 115 21, Athens, Greece.
Nikolaos NatsioulasDepartment of Orthopaedic Surgery, Naval Hospital of Athens, Deinokratous 70, 115 21, Athens, Greece.
Konstantinos BarbagiannisDepartment of Orthopaedic Surgery, Naval Hospital of Athens, Deinokratous 70, 115 21, Athens, Greece.
Panayiotis J Papagelopoulos1st Department of Orthopaedic Surgery, School of Medicine, National and Kapodistrian University of Athens, "ATTIKON" University General Hospital, 124 62, Athens, Greece.
Olga D Savvidou1st Department of Orthopaedic Surgery, School of Medicine, National and Kapodistrian University of Athens, "ATTIKON" University General Hospital, 124 62, Athens, Greece.
Athens Naval & Veterans Hospital · GRNational and Kapodistrian University of Athens · GRKlinik Sonnenhof · CHUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe increasing number of hip arthroplasties (HA), due to the growing elderly population, is associated with the risk of femoral periprosthetic fractures (FPFs). The purpose of this study was to identify potential risk factors for the development of FPFs after HA.

methodsA systematic review was conducted in five data bases (Medline, Embase, Cochrane, Cinahl, ICTRP) according to the Preferred Reporting Items for Systematic reviews and Meta-analysis (PRISMA) guidelines up to May 2019, using the key words "risk factor," "periprosthetic fracture," and "hip replacement or arthroplasty." Meta-analysis of the clinical outcomes of HA and subgroup analysis based on the factors that were implicated in FPFs was performed.

resultsSixteen studies were included (sample size: 599,551 HA patients, 4253 FPFs, incidence 0.71%). Risk factors statistically associated with increased incidence of FPFs were female gender (+ 40%), previous revision arthroplasty surgery (× 3 times), and the presence of rheumatoid arthritis (× 2.1 times), while osteoarthritis (- 57%), cement application (- 59%), and insertion of Biomet (- 68%) or Thompson's prosthesis (- 75%) were correlated with low prevalence of FPFs. Obesity, cardiac diseases, advanced age, bad general health (ASA grade ≥ 3), and use of Exeter or Lubinus prosthesis were not linked to the appearance of FPFs.

conclusionThis meta-analysis suggested that female gender, rheumatoid arthritis, and revision arthroplasty are major risk factors for the development of FPFs after a HA. In those patients, frequent follow-ups should be planned. Further prospective studies are necessary to clarify all the risk factors contributing to the appearance of FPFs after HA.

Indexed as

Arthritis, RheumatoidArthroplasty, Replacement, HipBone CementsDental Prosthesis, Implant-SupportedFemaleHumansIncidenceMaleOsteoarthritisPeriprosthetic FracturesPostoperative ComplicationsReoperationRisk FactorsSex FactorsBone CementsHip arthroplastyPeriprosthetic fracturesRisk factors

Identifiers

PMID33407704
PMCPMC7788804
OpenAlexW3119640797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.