Evidence map›Paper›PMID 33407612›Full record

ArticleJournal of translational medicine2021

Effects of time-restricted feeding in weight loss, metabolic syndrome and cardiovascular risk in obese women.

Jéssica D Schroder, Hugo Falqueto, Aline Mânica, Daniela Zanini, Tácio de Oliveira, Clodoaldo A de Sá, Andréia Machado Cardoso, Leandro Henrique Manfredi

Registry-linked trialOpen access · goldAbstract readControlled Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06139562 (Two Different Dietary Approaches In Body Composition And Serum Hormone Levels), which is not on this map. Cited by 77 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 4 pooled it
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06139562 nacompletednot on this map

Two Different Dietary Approaches In Body Composition And Serum Hormone Levels: Time-Restricted And Extended Feeding

TypeinterventionalSponsorBaskent UniversityRan2019 to 2020Enrolled20ConditionsTime Restricted Feeding, ObesityArmsTime-Restricted Feeding, Extended-Time Feeding
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 4 syntheses or guidelines pooled it, 141 citations in OpenAlex.

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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jéssica D SchroderMedical School, Federal University of Fronteira Sul, UFFS, SC 484 - Km 02, Fronteira Sul, Chapecó, Santa Catarina, 89815-899, Brazil.
Hugo FalquetoMedical School, Federal University of Fronteira Sul, UFFS, SC 484 - Km 02, Fronteira Sul, Chapecó, Santa Catarina, 89815-899, Brazil.ORCID 0000-0001-7546-297X
Aline MânicaHealth Science Department, Community University of the Region of Chapecó (UNOCHAPECÓ), Chapecó, SC, Brazil.
Daniela ZaniniMedical School, Federal University of Fronteira Sul, UFFS, SC 484 - Km 02, Fronteira Sul, Chapecó, Santa Catarina, 89815-899, Brazil.
Tácio de OliveiraGraduate Program in Biomedical Sciences, Federal University of Fronteira Sul, UFFS, SC 484 - Km 02, Fronteira Sul, Chapecó, Santa Catarina, Brazil.
Clodoaldo A de SáHealth Science Department, Community University of the Region of Chapecó (UNOCHAPECÓ), Chapecó, SC, Brazil.
Andréia Machado CardosoMedical School, Federal University of Fronteira Sul, UFFS, SC 484 - Km 02, Fronteira Sul, Chapecó, Santa Catarina, 89815-899, Brazil.ORCID 0000-0003-4243-8855
Leandro Henrique ManfrediMedical School, Federal University of Fronteira Sul, UFFS, SC 484 - Km 02, Fronteira Sul, Chapecó, Santa Catarina, 89815-899, Brazil. leandrohm@gmail.com.ORCID 0000-0002-4157-8613
Universidade Federal da Fronteira Sul · BRCommunity University of Chapecó Region - Unochapecó · BR

Funding

UFFS 480/GR/UFFS/2018
6 · The paper itself

Abstract

backgroundThe increasing prevalence of overweight and obesity among the worldwide population has been associated with a range of adverse health consequences such as Type 2 diabetes and cardiovascular diseases. The metabolic syndrome (MetS) is a cluster of cardiometabolic abnormalities that occur more commonly in overweight individuals. Time-restricted feeding (TRF) is a dietary approach used for weight loss and overall health. TRF may be an option for those subjects who struggle with extreme restriction diets with foods that generally do not belong to an individual's habits.

objectiveThe purpose of this study was to determine the effect of TRF on body composition and the association of weight loss with metabolic and cardiovascular risks in obese middle-aged women.

methodsA non-randomized controlled clinical trial was performed over 3 months in obese women (TRF group, n = 20, BMI 32.53 ± 1.13 vs. Control n = 12, BMI 34.55 ± 1.20). The TRF protocol adopted was 16 h without any energy intake followed by 8 h of normal food intake. MAIN OUTCOMES AND MEASURES: Anthropometric measurements, body composition, blood biomarkers, cardiovascular risk in 30 years (CVDRisk30y), and quality of life were evaluated at baseline and after the 3 months.

resultsTRF was effective in reducing weight (~ 4 kg), BMI, % of body fat (%BF), waist circumference from baseline without changes in blood biomarkers associated with MetS. TRF promoted a reduction in CVDRisk30y (12%) wich was moderately correlated with %BF (r = 0.62, n = 64, p < 0.001) and %MM (r = - 0.74, n = 64, p < 0.001).

conclusionsTRF protocol reduces body weight without changes in biomarkers related to MetS. In addition, the anthropometric evaluation that predicts %BF and %MM could be used as an approach to follow individuals engaged in the TRF regimen since they correlate with cardiovascular risk.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Metabolic SyndromeBody Mass IndexFemaleHeart Disease Risk FactorsHumansMiddle AgedObesityOverweightQuality of LifeRisk FactorsWeight LossAnthropometryCardiovascular riskIntermittent fastingMetabolic syndromeObesityTime-restricted feedingWeight loss

Identifiers

PMID33407612
PMCPMC7786967
OpenAlexW3118391367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.