Evidence map›Paper›PMID 33407536›Full record

ArticleAnnals of clinical microbiology and antimicrobials2021

First detection of a plasmid-encoded New-Delhi metallo-beta-lactamase-1 (NDM-1) producing Acinetobacter baumannii using whole genome sequencing, isolated in a clinical setting in Benin.

Carine Yehouenou, Bert Bogaerts, Kevin Vanneste, Nancy H C Roosens, Sigrid C J De Keersmaecker, Kathleen Marchal, Dissou Affolabi, Reza Soleimani, Hector Rodriguez-Villalobos, Françoise Van Bambeke and 2 more

Abstract readCase Reports
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Carbapenem-resistantMicrobiology spectrum · 2026
    Article
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carine YehouenouClinical Pharmacy Research Group (CLIP), Louvain Drug Research Institute (LDRI), Université Catholique de Louvain UCLouvain, Brussels, Belgium. yehcarine@yahoo.fr.ORCID http://orcid.org/0000-0003-0533-3165
Bert BogaertsSciensano, Transversal Activities in Applied Genomics, Brussels, Belgium. bert.bogaerts@sciensano.be.
Kevin VannesteSciensano, Transversal Activities in Applied Genomics, Brussels, Belgium.
Nancy H C RoosensSciensano, Transversal Activities in Applied Genomics, Brussels, Belgium.
Sigrid C J De KeersmaeckerSciensano, Transversal Activities in Applied Genomics, Brussels, Belgium.
Kathleen MarchalDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.
Dissou AffolabiLaboratoire de Référence des Mycobactéries (LRM), Cotonou, Benin.
Reza SoleimaniMicrobiologie, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, UCLouvain, Brussels, Belgium.
Hector Rodriguez-VillalobosMicrobiologie, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, UCLouvain, Brussels, Belgium.
Françoise Van BambekeClinical Pharmacy Research Group (CLIP), Louvain Drug Research Institute (LDRI), Université Catholique de Louvain UCLouvain, Brussels, Belgium.
Olivia DalleurClinical Pharmacy Research Group (CLIP), Louvain Drug Research Institute (LDRI), Université Catholique de Louvain UCLouvain, Brussels, Belgium.
Anne SimonMicrobiologie, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, UCLouvain, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarbapenem-resistant Acinetobacter baumannii is considered a top priority pathogen by the World Health Organization for combatting increasing antibiotic resistance and development of new drugs. Since it was originally reported in Klebsiella pneumoniae in 2009, the quick spread of the bla CASE PRESENTATION: A 31-year-old woman was admitted to a surgical unit with a diagnosis of post-cesarean hematoma. An extensively-drug resistant A. baumannii strain solely susceptible to amikacin, colistin and ciprofloxacin, and resistant to several other antibiotics including ceftazidime, imipenem, meropenem, gentamicin, tobramycin, ceftazidime/avibactam, and sulfamethoxazole-trimethoprim, was isolated from the wound. Production of NDM-1 was demonstrated by immunochromatographic testing. Whole genome sequencing of the isolate confirmed the presence of bla

conclusionsThe discovery of this extensively-drug resistant A. baumannii strain carrying bla

Indexed as

Acinetobacter baumanniiAdultbeta-LactamasesFemaleHumansPlasmidsWhole Genome Sequencingbeta-lactamase NDM-1beta-LactamasesAcinetobacter baumanniiBeninNew-Delhi metallo-beta-lactamaseWhole-genome sequencing

Identifiers

PMID33407536
PMCPMC7789245

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.