ArticleBMC women's health2021
Menstrual, reproductive and hormonal factors and thyroid cancer: a hospital-based case-control study in China.
Article in BMC women's health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Diverging spatiotemporal trajectories of thyroid cancer incidence and mortality in reproductive-age women: a socio-demographic index stratified analysis of GBD 2021 data.Gland surgery · 2025Article
- Reproductive and Hormonal Factors and Thyroid Cancer Risk: Pooled Analysis of Prospective Cohort Studies in the Asia Cohort Consortium.Cancer prevention research (Philadelphia, Pa.) · 2025Article
- Investigating papillary thyroid cancer risk factors among women living at the central region of Iran: a case-control study.BMC endocrine disorders · 2025Article
- Thyroid cancer and pregnancy: a systematic ten-year-review.Gland surgery · 2024Review
- The association between diabetes and thyroid cancer risk: a hospital-based case-control study in China.BMC endocrine disorders · 2021Article
- Thyroid Cancer Burden in China: 1990 to 2021 Trends and 15-Year Projections Against Global Trends.OTO openArticle
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Authors and funding
5 authors.
Funding
Abstract
backgroundThere have been considerable studies on the effects of reproductive factors on thyroid cancer risk, while findings are inconsistent. In this analysis, we aimed to investigate the associations between menstrual, reproductive and hormonal factors with thyroid cancer occurrence in a population of Chinese women.
methodsUsing data from a 1:1 matched case-control study performed between 2015 and 2017 in Zhejiang Province of China, a second analysis of 2261 pairs of female subjects was conducted. The possible effects for thyroid cancer were evaluated in logistic regression models by odds ratios (ORs) with 95% confidence intervals (CIs).
resultsLater age at first pregnancy (for > 25 vs. ≦ 20 years, OR: 0.47, 95% CI 0.23-0.96) and longer duration of breast feeding (for 6-12 vs. ≦ 6 months, OR: 0.49, 95% CI 0.24-0.98) were significantly associated with decreased occurrence of thyroid cancer, while no trend was observed. Stratified by age at enrollment, only the association with duration of breast feeding remained significant, but limited to younger women (≦ 50 years).
conclusionsOur results suggested that women with later age at first pregnancy or longer breast feeding duration were less likely to have thyroid cancer. These findings supported an influence role of reproductive factors in thyroid cancer risk.
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