Trial reportBMC geriatrics2021
Physical exercise for individuals with dementia: potential benefits perceived by formal caregivers.
Trial report in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04095962 (Body and Brain), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Body and Brain: Effects of a Multicomponent Exercise Intervention on Physical and Cognitive Function of Older Adults With Dementia
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Effectiveness of physical rehabilitation for physical functioning and quality of life in long-term care residents with dementia: a systematic review and meta-analysis.JBI evidence synthesis · 2024Pooled it
- Trial
- Effects of combined group reminiscence and exercise therapy on psychological wellbeing and functional fitness among older adults with dementia.Scientific reports · 2025Trial
- Non-Pharmacological Interventions for Managing Apathy in Older Adults with Neurocognitive Disorders: A Systematic Review of Randomized Controlled Trials.Brain sciences · 2026Review
- Factors Associated With Physical Activity in Alzheimer's Disease: A Cross-Sectional Study of Individuals and Their Caregivers.Journal of aging and health · 2026Article
- Review
- Enhancing empathy and attitudes toward dementia among formal caregivers through virtual reality: a randomized controlled trial.Innovation in aging · 2026Article
- Article
- Finding the way - nursing staff's perceptions and experiences of outdoor walks with residents in dementia care homes: a qualitative study.BMC nursing · 2025Article
- Comparison of the relationship between key demographic features and physical activity levels across 22 countries.BMC public health · 2025Article
- A study on the effectiveness of individual centered goal-oriented cognitive rehabilitation in vascular dementia.Cerebral circulation - cognition and behavior · 2025Article
- Nutritional Modulation of the Gut-Brain Axis: A Comprehensive Review of Dietary Interventions in Depression and Anxiety Management.Metabolites · 2024Review
- Psychosocial factors associated with physical activity in people with dementia: A pilot cross-sectional study.Aging medicine (Milton (N.S.W)) · 2024Article
- Technology-based group exercise interventions for people living with dementia or mild cognitive impairment: A scoping review.PloS one · 2024Article
- Neuropsychiatric Symptoms are Related to Blood-biomarkers in Major Neurocognitive Disorders.Current aging science · 2024Article
- Enhancing Minds in Motion® as a virtual program delivery model for people living with dementia and their care partners.PloS one · 2024Article
- Promoting Physical Activity in a Primary Care Practice in People Living with Dementia and Their Family Caregivers.Healthcare (Basel, Switzerland) · 2023Article
- Alzheimer's Disease-Biochemical and Psychological Background for Diagnosis and Treatment.International journal of molecular sciences · 2023Review
- Exercise therapy to prevent and treat Alzheimer's disease.Frontiers in aging neuroscience · 2023Review
- Non-Pharmacological Interventions for Wandering/Aberrant Motor Behaviour in Patients with Dementia.Brain sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe social and economic impact of dementia for the development of accessible and sustainable care for individuals with dementia (IwD). Physical exercise has been seen as a beneficial non-pharmacological therapy in the prevention and management of dementia, and possible benefits may not only impact on participants, but also indirectly on their caregivers. Thus, this quasi-experimental non-randomized study aimed to analyze the effects of an exercise intervention on functional capacity, behavioural and psychological symptoms in dementia (BPSD) and quality of life of institutionalized older adults with dementia, perceived by their formal caregivers.
methodsSixty-four institutionalized older adults (from both genders, aged 65-93 yrs. old), clinically diagnosed with dementia, were divided into two groups: control group (CG, continued with usual care, n = 26) and exercise group (EG, 6-month supervised multicomponent exercise intervention, n = 38). Nine caregivers (female, aged 28-47 yrs. old) from nine different nursing homes, reported about their distress related to BPSD and proxy-reported about participants' functional capacity (Katz index), quality of life (QoL-AD), BPSD (NPI) before and after 6 months of an exercise intervention (aerobic, muscular resistance, flexibility and postural exercises).
resultsA two-way ANOVA, with repeated measures, revealed significant group and time interactions on Total Katz index and QoL-AD. The CG's performance functional capacity and quality of life score worsen over time while in EG maintains these values after the exercise intervention. Moreover, formal caregiver's distress triggered by apathy and disinhibition increased in CG while after 6 months of an exercise intervention no alterations were seen regarding these distress causes in EG. No significant main effects were observed for total NPI score or NPI distress.
conclusionsOverall results show that after the exercise intervention, IwD from the EG, was capable of preserving the functional capacity, quality of life and neuropsychiatric symptoms were attenuate, contributing to a lower load of distress for the caregivers.
trial registrationclinicaltrials.gov , NCT04095962 . Retrospectively registered on 19 September 2019.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.