Evidence map›Paper›PMID 33407192›Full record

ReviewBMC infectious diseases2021

Klebsiella pneumoniae-related invasive liver abscess syndrome complicated by purulent meningitis: a review of the literature and description of three cases.

Ruixue Sun, Hui Zhang, Yingchun Xu, Huadong Zhu, Xuezhong Yu, Jun Xu

Abstract readCase ReportsReview
In one paragraph

Review in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Antibiotics accumulate inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Infection and immunity · 2025
    Review
  8. Diagnostics (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
  11. Case report: InvasiveFrontiers in medicine · 2025
    Article
  12. Article
  13. Purulent Meningitis Due toInfection and drug resistance · 2025
    Article
  14. Article
  15. Blindness in Right Eyes after Enema: A Case ofCase reports in medicine · 2024
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruixue SunEmergency Department, Peking Union Medical College Hospital, No.1 shuaifuyuan, Dongcheng District, Beijing, China.
Hui ZhangLaboratory Department, Peking Union Medical College Hospital, No.1 shuaifuyuan, Dongcheng District, Beijing, China.
Yingchun XuLaboratory Department, Peking Union Medical College Hospital, No.1 shuaifuyuan, Dongcheng District, Beijing, China.
Huadong ZhuEmergency Department, Peking Union Medical College Hospital, No.1 shuaifuyuan, Dongcheng District, Beijing, China.
Xuezhong YuEmergency Department, Peking Union Medical College Hospital, No.1 shuaifuyuan, Dongcheng District, Beijing, China.
Jun XuEmergency Department, Peking Union Medical College Hospital, No.1 shuaifuyuan, Dongcheng District, Beijing, China. pumchxujun@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKlebsiella pneumoniae (K. pneumoniae) invasive liver abscess syndrome (ILAS) with purulent meningitis was rarely identified the mainland of China. Last winter, we received 3 cases of K. pneumoniae meningitis and all of them died in a short time. We report these cases in order to find the reason of high mortality and discuss effective effort to improve these patients' prognosis. CASE PRESENTATION: Three patients with uncontrolled diabetes developed live abscess and purulent meningitis. Upon admission, the clinical manifestations, laboratory result of blood and cerebrospinal fluid (CSF) and imaging examinations were compatible with K. pneumoniae ILAS which had metastasis infection of meningitis. Even with timely adequate antibiotic therapy and strict glycemic control, all of the patients' condition deteriorated rapidly and died in a short time.

conclusionThe reason of patients' poor prognosis might be the absence of liver abscess drainage, high level of CSF protein which indicates severe inflammation and unknown special but stronger virulence factors of K. pneumoniae the patients' living place Zhangjiakou. Strict glycemic control, early drainage of liver abscess and appropriate antibiotic application are recommended for treating this condition, further progress on the pathogenesis and treatment of K. pneumoniae meningitis may help patients gain a better prognosis.

Indexed as

AdultAnti-Bacterial AgentsChinaFatal OutcomeFemaleHumansKlebsiella InfectionsKlebsiella pneumoniaeLiver AbscessMaleMeningitis, BacterialMiddle AgedPrognosisSyndromeAnti-Bacterial AgentsCase reportKlebsiella pneumoniaeLiver abscessMeningitis

Identifiers

PMID33407192
PMCPMC7788956

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.