Evidence map›Paper›PMID 33407178›Full record

ArticleBMC gastroenterology2021

Metabolic syndrome components and acute pancreatitis: a case-control study in China.

Zhemin Shen, Xueqiao Wang, Zili Zhen, Yao Wang, Peilong Sun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

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  19. Fatty liver disease and pancreatic inflammation-A lethal combination?United European gastroenterology journal · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhemin ShenDepartment of General Surgery, Jinshan Hospital, Fudan University, Shanghai, China.
Xueqiao WangDepartment of Otorhinolaryngology Head and Neck Surgery, Jinshan Hospital, Fudan University, Shanghai, China.
Zili ZhenDepartment of General Surgery, Jinshan Hospital, Fudan University, Shanghai, China.
Yao WangDepartment of Orthopedics, Jinshan Hospital, Fudan University, Shanghai, China.
Peilong SunDepartment of General Surgery, Jinshan Hospital, Fudan University, Shanghai, China. sunpeilong@fudan.edu.cn.
Jinshan Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute pancreatitis (AP) is a common inflammatory disorder of the pancreas. Recent evidence has shown that metabolic syndrome is positively correlated with the severity of AP. However, only a few studies have revealed the relationship between metabolic syndrome and the occurrence of AP. We therefore elucidated the association between metabolic syndrome and the occurrence of AP.

methodsA hospital-based case-control study was conducted. A total of 705 patients admitted to our hospital from January 2016 to December 2018 were included in the study. Subjects were divided into case and control groups according to their diagnosis: (1) According to the revised Atlanta classification from 2012, patients diagnosed with AP were enrolled in the case group. (2) Patients without a history of AP or any disease related to metabolic syndrome were allocated into the control group. Controls were matched to cases individually by sex and age (control/case ratio = 1).

resultsThe incidence rate of metabolic syndrome in AP patients was 30.9%, which was more frequent than that in controls (13.2%) (OR 2.837; 95% CI 1.873-4.298, p < 0.001). In the multivariate regression analysis, a history of smoking or alcohol consumption and biliary stones were significantly associated with AP (OR 2.441; 95% CI 1.865-5.172, p < 0.001; OR 1.777; 95% CI 1.060-2.977, p = 0.029; OR 28.995; 95% CI 13.253-63.435, p < 0.001). In addition, the occurrence of AP was significantly associated with total cholesterol (TC) (OR 1.992; 95% CI 1.246-3.183, p = 0.004), triglyceride (TG) (OR 2.134; 95% CI 1.403-3.245, p < 0.001), hyperglycaemia (OR 2.261; 95% CI 1.367-3.742, p = 0.001), and apolipoprotein A (Apo A) (OR 0.270; 95% CI 0.163-0.447, p < 0.001).

conclusionsMetabolic syndrome and its components were associated with AP occurrence.

Indexed as

Metabolic SyndromePancreatitisAcute DiseaseCase-Control StudiesChinaHumansRetrospective StudiesSeverity of Illness IndexAcute pancreatitisHyperglycaemiaHyperlipidaemiaHypertensionMetabolic syndromeObesity

Identifiers

PMID33407178
PMCPMC7789414
OpenAlexW3116851276

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.