ArticleBMC plant biology2021
The NAC-type transcription factor CaNAC46 regulates the salt and drought tolerance of transgenic Arabidopsis thaliana.
Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39 citing papers in PubMed, 87 citations in OpenAlex.
- Molecular mechanisms and agronomic strategies for thermotolerance in chili pepper (Capsicum annuum L.).Plant cell reports · 2026Review
- Comprehensive genome-wide mining and characterization of the NAC transcription factor family in Gynostemma pentaphyllum identifies GpNAC68 as a positive regulator of drought tolerance in transgenic Arabidopsis.BMC plant biology · 2026Article
- Genome-wide analysis of the NAC gene family in Qu-1 doubled haploid cell line from Populus simonii × P. nigra and expression patterns under abscisic acid (ABA) treatment.BMC plant biology · 2026Article
- Global profiling of alternative splicing landscapes in response to cold stress during the cotyledon stage in cotton.BMC genomics · 2026Article
- Construction of a single-cell transcriptome atlas for Pogostemon cablin embryoids reveals PcNAC048 as a dual regulator coordinating lateral root morphogenesis and patchouli alcohol biosynthesis.Communications biology · 2025Article
- Overexpression ofPlants (Basel, Switzerland) · 2025Article
- Physiological response of safflower to water deficit and genome-wide identification of its NAC transcription factor family.Scientific reports · 2025Article
- Strategies to develop climate-resilient chili peppers: transcription factor optimization through genome editing.Planta · 2025Review
- Isolation and Expression Pattern Analysis ofPlants (Basel, Switzerland) · 2025Article
- Growing vegetables in a warming world - a review of crop response to drought stress, and strategies to mitigate adverse effects in vegetable production.Frontiers in plant science · 2025Review
- Lead toxicity in plants: mechanistic insights into toxicity, physiological responses of plants and mitigation strategies.Plant signaling & behavior · 2024Review
- The White Clover Single-Copy Nuclear GenePlants (Basel, Switzerland) · 2024Article
- Deciphering Drought Resilience in Solanaceae Crops: Unraveling Molecular and Genetic Mechanisms.Biology · 2024Review
- Overexpression of rice High-affinity Potassium Transporter gene OsHKT1;5 improves salinity and drought tolerance in Arabidopsis.Molecular biology reports · 2024Article
- Physiological and Genetic Aspects of Resistance to Abiotic Stresses inPlants (Basel, Switzerland) · 2024Review
- Expression Patterns and Molecular Mechanisms Regulating Drought Tolerance of Soybean [International journal of molecular sciences · 2024Article
- Role of transcriptional regulation in auxin-mediated response to abiotic stresses.Frontiers in genetics · 2024Review
- Metabolomics Study of the Effect of Transcription Factor NOR-like1 on Flavonoids in Tomato at Different Stages of Maturity Using UPLC-MS/MS.Foods (Basel, Switzerland) · 2023Article
- The Functions of an NAC Transcription Factor, GhNAC2-A06, in Cotton Response to Drought Stress.Plants (Basel, Switzerland) · 2023Article
- Reactive Oxygen Species: A Crosslink between Plant and Human Eukaryotic Cell Systems.International journal of molecular sciences · 2023Review
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5 authors at 1 institution in 1 country.
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Abstract
backgroundThe NAC (NAM, ATAF1/ATAF2, and CUC2) transcription factors belong to a large family of plant-specific transcription factors in monocot and dicot species. These transcription factors regulate the expression of stress tolerance-related genes that protect plants from various abiotic stresses, including drought, salinity, and low temperatures.
resultsIn this study, we identified the CaNAC46 transcription factor gene in Capsicum annuum. Its open reading frame was revealed to comprise 921 bp, encoding a protein consisting of 306 amino acids, with an isoelectric point of 6.96. A phylogenetic analysis indicated that CaNAC46 belongs to the ATAF subfamily. The expression of CaNAC46 was induced by heat, cold, high salt, drought, abscisic acid, salicylic acid, and methyl jasmonate treatments. Thus, CaNAC46 may be important for the resistance of dry pepper to abiotic stresses. A subcellular localization analysis confirmed that CaNAC46 is localized in the nucleus. The overexpression of CaNAC46 improved the tolerance of transgenic Arabidopsis thaliana plants to drought and salt stresses. The CaNAC46-overexpressing lines had longer roots and more lateral roots than wild-type lines under prolonged drought and high salt stress conditions. Additionally, CaNAC46 affected the accumulation of reactive oxygen species (ROS). Moreover, CaNAC46 promoted the expression of SOD, POD, RD29B, RD20, LDB18, ABI, IAA4, and P5CS. The malondialdehyde contents were higher in TRV2-CaNAC46 lines than in wild-type plants in response to drought and salt stresses. Furthermore, the expression levels of stress-responsive genes, such as ABA2, P5CS, DREB, RD22, CAT, and POD, were down-regulated in TRV2-CaNAC46 plants.
conclusionsUnder saline and drought conditions, CaNAC46 is a positive regulator that activates ROS-scavenging enzymes and enhances root formation. The results of our study indicate CaNAC46 is a transcriptional regulator responsible for salinity and drought tolerance and suggest the abiotic stress-related gene regulatory mechanisms controlling this NAC transcription factor are conserved between A. thaliana and pepper.
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